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How to get fromChampaign to Mayo Clinicby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Mayo Clinic

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There are 6 ways to get from Champaign to Mayo Clinic by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from University Of Illinois Willard Airport (CMI) to Rochester (RST)plane plane CMI - RST
    6h 53m
    $74–402

  2. Bus via Milwaukee

    1. Take the bus from Champaign Intermodal Trans Ctr to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    11h 53m
    $128–183

  3. Train, bus

    1. Take the train from Champaign-Urbana to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    13h 40m
    $161–381

  4. Drive  417.6 mi

    1. Drive from Champaign to Mayo Cliniccar car 417.6 mi
    7h 57m
    $77–111

  5. Train, bus via Madison

    1. Take the train from Champaign-Urbana to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 22m
    $108–211

  6. Bus

    1. Take the bus from Champaign Intermodal Trans Ctr to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Madisonbus bus
    3. Take the bus from Madison to Rochesterbus bus
    14h 3m
    $101–154

Champaign to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration11h 53mAverage Duration
Ticket$128Cheapest Price
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Comparing Your Travel Options

Map of how to get from Champaign to Mayo Clinic.ExpandLaunch map view
  • Distance: 360 mi
  • Duration: 6h 53m

What companies run services between Champaign, IL, USA and Mayo Clinic, MN, USA?

American Airlines flies from University Of Illinois Willard Airport (CMI) to Rochester (RST) 3 times a day. Alternatively, you can take a bus from Champaign Intermodal Trans Ctr to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 11h 53m.

Airlines
Train operators
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