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How to get fromChapel Hill to Buffaloby bus, plane, bus (Flixbus), train (Amtrak), car, bus (Greyhound), or train

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There are 8 ways to get from Chapel Hill to Buffalo by bus, plane, bus (Flixbus), train (Amtrak), car, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 800 bus to Raleigh-Durham International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from S Columbia St at Health Sciences Library to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    5h 2m
    $130–244

  2. Drive  591.1 mi

    cheapest
    1. Drive from Chapel Hill to Buffalocar car 591.1 mi
    12h 23m
    $101–146

  3. Bus (Flixbus)

    1. Take the bus from Durham to New York Midtownbus bus FlixBus N2471 / ...
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    21h 21m
    $158–242

  4. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Carolinian
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    22h 27m
    $542–842

  5. Fly Raleigh-Durham International Airport to Rochester, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Rochester (ROC)plane plane RDU - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 17m
    $164–848

  6. Bus to Piedmont Triad International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF)plane plane GSO - BUF
    7h 46m
    $124–650

  7. Bus via New York

    1. Take the bus from Durham to Port Authority Bus Terminalbus bus Greyhound US0670
    2. Take the bus from Port Authority Bus Terminal to Buffalobus bus Greyhound US0215 / ...
    24h 32m
    $158–412

  8. Train, bus

    1. Take the train from Cary to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    26h 38m
    $380–746

Chapel Hill to Buffalo by bus (Flixbus)

Calendar22Weekly Buses
Duration21h 21mAverage Duration
Ticket$158Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chapel Hill to Buffalo.ExpandLaunch map view
  • Distance: 516.3 mi
  • Duration: 5h 2m

What companies run services between Chapel Hill, Orange County, NC, USA and Buffalo, NY, USA?

You can take a bus from E Franklin St at Coffee Shop to Buffalo via Durham Station, Durham, and New York Midtown in around 21h 21m. Alternatively, you can take a bus from E Franklin St at Coffee Shop to Buffalo via Chapel Hill St at Duke St, Durham Amtrak Station, and Ny Moynihan Train Hall At Penn Station in around 22h 27m.

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