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How to get fromChapel Hill to Des Moinesby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 6 ways to get from Chapel Hill to Des Moines by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Raleigh-Durham International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM)plane plane RDU - DSM
    6h 32m
    $192–826

  2. Bus

    1. Take the bus from Durham to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    29h 42m
    $212–422

  3. Bus, train

    1. Take the bus from South Rd at Fetzer Gym to Union Station - Bus Platform Bbus bus Crx
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    34h 47m

  4. Drive 1,046.9 mi

    1. Drive from Chapel Hill to Des Moinescar car 1,046.9 mi
    18h 18m
    $192–276

  5. Bus to Piedmont Triad International Airport, fly

    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Des Moines (DSM)plane plane GSO - DSM
    7h 33m
    $226–992

  6. Bus, train via Galesburg

    1. Take the bus from South Rd at Fetzer Gym to Union Station - Bus Platform Bbus bus Crx
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    35h 59m
    $432–878

Chapel Hill to Des Moines by bus

Calendar7Weekly Buses
Duration29h 42mAverage Duration
Ticket$212Cheapest Price
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Questions & Answers

Map of how to get from Chapel Hill to Des Moines.ExpandLaunch map view
  • Distance: 915.4 mi
  • Duration: 6h 32m

What companies run services between Chapel Hill, Orange County, NC, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM) hourly. Alternatively, you can take a bus from E Franklin St at Coffee Shop to Des Moines via Durham Station, Durham, Atlanta Bus Station, and St Louis Bus Station in around 29h 42m.

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