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How to get fromChapel Hill to Louisvilleby bus, plane, train, car, or bus (Flixbus, Greyhound, Amtrak)

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There are 6 ways to get from Chapel Hill to Louisville by bus, plane, train, car, or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 800 bus to Raleigh-Durham International Airport, fly

    best
    1. Take the bus from S Columbia St at Health Sciences Library to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    5h 3m
    $102–558

  2. Bus

    cheapest
    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus 4
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    18h 42m
    $62–156

  3. Bus, train

    1. Take the bus from Columbia & Rosemary to Greensboro Depotbus bus 4
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    25h 43m
    $270–568

  4. Drive 491.3 mi

    1. Drive from Chapel Hill to Louisvillecar car 491.3 mi
    9h 28m
    $90–130

  5. Bus to Piedmont Triad International Airport, fly

    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Louisville International Airport (SDF)plane plane GSO - SDF
    7h 32m
    $130–674

  6. Bus via Atlanta

    1. Take the bus from Durham to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    19h 17m
    $122–248

Chapel Hill to Louisville by bus

Calendar14Weekly Buses
Duration19h 17mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Chapel Hill to Louisville.ExpandLaunch map view
  • Distance: 440.4 mi
  • Duration: 5h 3m

What companies run services between Chapel Hill, Orange County, NC, USA and Louisville, KY, USA?

You can take a bus from Columbia & Rosemary to Louisville, KY Bus Station via Coble Transportation Center, Winston-Salem Transportation Center, Winston Salem(Trans Center), and Columbus - Downtown - Mound St in around 18h 42m.

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