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How to get fromChapel Hill to St. Louisby bus, plane, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

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There are 6 ways to get from Chapel Hill to St. Louis by bus, plane, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 800 bus to Raleigh-Durham International Airport, fly

    best
    1. Take the bus from S Columbia St at Health Sciences Library to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    5h 13m
    $558–1,108

  2. Bus via Columbus

    cheapest
    1. Take the bus from Columbia & Rosemary to Greensboro Depotbus bus 4
    2. Take the bus from Greensboro to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to St Louis Bus Stationbus bus
    23h 30m
    $114–212

  3. Bus

    1. Take the bus from Durham to Atlanta Downtownbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    21h 6m
    $146–246

  4. Bus, train

    1. Take the bus from South Rd at Fetzer Gym to Union Station - Bus Platform Bbus bus Crx
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    32h 14m
    $368–952

  5. Drive  749.8 mi

    1. Drive from Chapel Hill to St. Louiscar car 749.8 mi
    13h 45m
    $137–198

  6. Bus to Piedmont Triad International Airport, fly

    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    7h 39m
    $132–674

Chapel Hill to St. Louis by bus and subway

Calendar4Weekly Services
Duration21h 6mAverage Duration
Ticket$146Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chapel Hill to St. Louis.ExpandLaunch map view
  • Distance: 698.7 mi
  • Duration: 5h 13m

What companies run services between Chapel Hill, Orange County, NC, USA and St. Louis, MO, USA?

You can take a bus from E Franklin St at Coffee Shop to St Louis Bus Station via Durham Station, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 21h 6m.

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