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How to get fromChapel Hill to St. Louisby bus, plane, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

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There are 6 ways to get from Chapel Hill to St. Louis by bus, plane, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 800 bus to Raleigh-Durham International Airport, fly

    best
    1. Take the bus from S Columbia St at Health Sciences Library to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    5h 3m
    $558–1,008

  2. Bus via Columbus

    cheapest
    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus 4
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to St Louis Bus Stationbus bus
    23h 12m
    $136–236

  3. Bus

    1. Take the bus from Durham to Atlanta Bus Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    20h 12m
    $148–292

  4. Bus, train

    1. Take the bus from South Rd at Fetzer Gym to Union Station - Bus Platform Bbus bus Crx
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    32h 14m
    $432–892

  5. Drive 749.8 mi

    1. Drive from Chapel Hill to St. Louiscar car 749.8 mi
    13h 43m
    $137–198

  6. Bus to Piedmont Triad International Airport, fly

    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    7h 36m
    $162–774

Chapel Hill to St. Louis by bus

Calendar19Weekly Buses
Duration20h 12mAverage Duration
Ticket$148Cheapest Price
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Questions & Answers

Map of how to get from Chapel Hill to St. Louis.ExpandLaunch map view
  • Distance: 698.7 mi
  • Duration: 5h 3m

What companies run services between Chapel Hill, Orange County, NC, USA and St. Louis, MO, USA?

You can take a bus from E Franklin St at Coffee Shop to St Louis Bus Station via Durham Station, Durham, and Atlanta Bus Station in around 20h 12m.

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