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How to get fromCharleston Airport (CHS) to Mayo Clinicby plane, car, or bus

Find Transport to Mayo Clinic

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There are 4 ways to get from Charleston Airport (CHS) to Mayo Clinic by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Charleston International Airport (CHS) to Rochester (RST)plane plane CHS - RST
    6h 28m
    $99–504

  2. Drive 1,213.5 mi

    1. Drive from Charleston-Airport-CHS to Mayo Cliniccar car 1,213.5 mi
    21h 33m
    $222–320

  3. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Minneapolis–Saint Paul International Airport (MSP)plane plane CHS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 53m
    $176–634

  4. Fly to La Crosse, bus

    1. Fly from Charleston International Airport (CHS) to La Crosse (LSE)plane plane CHS - LSE
    2. Take the bus from Landline - La Crosse Regional Airport to Landline - MSP Terminal-2 Humphreybus bus
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    11h 38m
    $184–563

Charleston International Airport (CHS) to Rochester (RST) flights

Calendar21Weekly Planes
Duration7h 1mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Charleston Airport (CHS) to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,024.4 mi
  • Duration: 6h 28m

What companies run services between Charleston Airport (CHS), USA and Mayo Clinic, MN, USA?

American Airlines and Delta fly from Charleston International Airport (CHS) to Rochester (RST) 3 times a day.

Airlines
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