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How to get fromCharleston Amtrak Station to Florida Keysby plane, train, bus, car, or shuttle

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There are 6 ways to get from Charleston Amtrak Station to Florida Keys by plane, train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charleston International Airport to Key West International Airport

    best
    1. Fly from Charleston International Airport (CHS) to Key West International Airport (EYW)plane plane CHS - EYW
    8h 35m
    $349–596

  2. Drive 726.5 mi

    cheapest
    1. Drive from Charleston Amtrak Station to Florida Keyscar car 726.5 mi
    12h 51m
    $133–192

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    20h 42m
    $232–475

  4. Fly Charleston International Airport to Miami International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 9m
    $654–1,186

  5. Fly Charleston International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 40m
    $344–1,306

  6. Train to Savannah, fly to Miami International Airport, shuttle

    1. Take the train from Charleston Amtrak Station to Savannah Stationtrain train
    2. Fly from Savannah (SAV) to Miami International Airport (MIA)plane plane SAV - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 6m
    $300–751

Charleston Amtrak Station to Florida Keys by train, bus, and foot

Calendar7Weekly Services
Duration20h 42mAverage Duration
Ticket$232Cheapest Price
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Questions & Answers

Map of how to get from Charleston Amtrak Station to Florida Keys.ExpandLaunch map view
  • Distance: 611.6 mi
  • Duration: 8h 35m

What companies run services between Charleston Amtrak Station, SC, USA and Florida Keys, FL, USA?

American Airlines and Delta fly from Charleston International Airport (CHS) to Key West International Airport (EYW) 5 times a day.

Airlines
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