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How to get fromCharleston Amtrak Station to Key Westby plane, train, shuttle, car, bus, or taxi

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There are 6 ways to get from Charleston Amtrak Station to Key West by plane, train, shuttle, car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charleston International Airport

    best
    1. Fly from Charleston International Airport (CHS) to Key West International Airport (EYW)plane plane CHS - EYW
    5h 48m
    $283–515

  2. Drive 742 mi

    cheapest
    1. Drive from Charleston Amtrak Station to Key Westcar car 742 mi
    13h 14m
    $136–196

  3. Train, shuttle

    1. Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain train Silver Meteor
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus To the Keys
    21h 12m
    $388–645

  4. Train to Savannah, fly

    1. Take the train from Charleston Amtrak Station to Savannah Stationtrain train
    2. Fly from Savannah (SAV) to Key West International Airport (EYW)plane plane SAV - EYW
    6h 53m
    $444–780

  5. Bus to Myrtle Beach, fly

    1. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane plane MYR - EYW
    7h 45m
    $387–656

  6. Train, taxi to Hilton Head Airport, fly

    1. Take the train from Charleston Amtrak Station to Savannah Stationtrain train
    2. Take the taxi from Savannah Station to Hilton Head Airport (HHH)taxi taxi
    3. Fly from Hilton Head Airport (HHH) to Key West International Airport (EYW)plane plane HHH - EYW
    8h 17m
    $264–620

Charleston Amtrak Station to Key West by train, foot, tram, shuttle, and bus

Calendar7Weekly Services
Duration21h 12mAverage Duration
Ticket$388Cheapest Price
See schedules

Questions & Answers

Map of how to get from Charleston Amtrak Station to Key West.ExpandLaunch map view
  • Distance: 592.4 mi
  • Duration: 5h 48m

What companies run services between Charleston Amtrak Station, SC, USA and Key West, FL, USA?

American Airlines and Delta fly from Charleston International Airport (CHS) to Key West International Airport (EYW) 5 times a day.

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