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How to get fromCharleston Amtrak Station to Port Saint Lucieby train, bus, car, or plane

Find Transport to Port Saint Lucie

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There are 7 ways to get from Charleston Amtrak Station to Port Saint Lucie by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Charleston Amtrak Station to Kissimmee Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus Orlando to Miami
    12h 17m
    $158–306

  2. Drive 472.5 mi

    cheapest
    1. Drive from Charleston Amtrak Station to Port Saint Luciecar car 472.5 mi
    8h 2m
    $87–125

  3. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    7h 22m
    $262–1,147

  4. Train, bus via DeLand

    1. Take the train from Charleston Amtrak Station to Delandtrain train
    2. Take the train from DeLand to LYNX Centraltrain train
    3. Take the bus from Orlando to Port St Luciebus bus
    14h 7m
    $131–264

  5. Fly to Miami International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    2. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    7h 37m
    $525–1,048

  6. Fly to Orlando, line 18 bus, bus

    1. Fly from Charleston International Airport (CHS) to Orlando (MCO)plane plane CHS - MCO
    2. Take the bus from Office Ct & Sand Lake Sunrail to Osceola Pkwy Walmartbus bus
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    7h 56m
    $101–306

  7. Fly to President Donald J. Trump International Airport, bus

    1. Fly from Charleston International Airport (CHS) to President Donald J. Trump International Airport (PBI)plane plane CHS - PBI
    2. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    7h 58m
    $121–768

Charleston Amtrak Station to Port Saint Lucie by train and bus

Calendar7Weekly Services
Duration12h 17mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Charleston Amtrak Station to Port Saint Lucie.ExpandLaunch map view
  • Distance: 523.5 mi
  • Duration: 12h 17m

What companies run services between Charleston Amtrak Station, SC, USA and Port Saint Lucie, FL, USA?

There is no direct connection from Charleston Amtrak Station to Port Saint Lucie. However, you can take the train to Kissimmee Amtrak Station, walk to Pleasant St & Neptune Rd, take the line 18 bus to Osceola Pkwy Walmart, walk to Kissimmee -1471 East Osceola Parkway, then take the bus to Fort Pierce. Alternatively, you can drive from Charleston Amtrak Station to Port Saint Lucie in around 8h 2m.

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