Rome2Rio

How to get fromCharleston to Buffaloby plane, train (Amtrak), car, bus, or train

Find Transport to Buffalo

See all options

There are 6 ways to get from Charleston to Buffalo by plane, train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charleston International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Charleston International Airport (CHS) to Buffalo Niagara International Airport (BUF)plane plane CHS - BUF
    4h 45m
    $139–736

  2. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Palmetto / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    23h 56m
    $671–1,066

  3. Drive  858.5 mi

    1. Drive from Charleston to Buffalocar car 858.5 mi
    14h 41m
    $152–220

  4. Fly Charleston International Airport to Rochester, bus

    1. Fly from Charleston International Airport (CHS) to Rochester (ROC)plane plane CHS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 16m
    $203–954

  5. Drive to Hilton Head Airport, fly to Buffalo Niagara International Airport

    1. Drive from Charleston to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Buffalo Niagara International Airport (BUF)plane plane HHH - BUF
    8h 4m
    $143–704

  6. Train, bus

    1. Take the train from Charleston Amtrak Station to Newark Penn Stationtrain train Palmetto / ...
    2. Take the bus from Newark Penn Station to Buffalobus bus FlixBus 2686 / ...
    25h 11m
    $459–764

Charleston to Buffalo by bus and train

Calendar14Weekly Services
Duration25h 11mAverage Duration
Ticket$459Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Charleston to Buffalo.ExpandLaunch map view
  • Distance: 719.3 mi
  • Duration: 4h 45m

What companies run services between Charleston, SC, USA and Buffalo, NY, USA?

Breeze Airways, American Airlines, and three other airlines fly from Charleston International Airport (CHS) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a vehicle from Charleston to Buffalo via Charleston Amtrak Station and Ny Moynihan Train Hall At Penn Station in around 23h 56m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There