There are 5 ways to get from Charleston to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport
best- Fly from Charleston International Airport (CHS) to Chicago Midway International Airport (MDW)plane CHS - MDW
4h 15m$87–458Train (Amtrak)
- Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain Silver Meteor / ...
- Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain Floridian
29h 10m$371–946Bus
- Take the bus from Charleston Bus Station to Atlanta Bus Stationbus Greyhound US0641S
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus Greyhound US0100
31h 3m$179–314Drive 873.5 mi
- Drive from Charleston to Chicagocar 873.5 mi
15h 58m$160–231Fly to Chicago O'Hare International Airport
- Fly from Charleston International Airport (CHS) to Chicago O'Hare International Airport (ORD)plane CHS - ORD
4h 41m$597–775
Charleston to Chicago by bus
Comparing Your Travel Options
The cheapest way to get from Charleston to Chicago is to drive which costs $150 - $230 and takes 15h 58m.
The fastest way to get from Charleston to Chicago is to fly which takes 4h 15m and costs $85 - $460.
No, there is no direct bus from Charleston to Chicago station. However, there are services departing from Mary St / Meeting St and arriving at Chicago Bus Station via N. Charleston SuperStop, Charleston Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 31h 3m.
No, there is no direct train from Charleston station to Chicago station. However, there are services departing from Charleston Amtrak Station and arriving at Chicago Union Station via Petersburg Amtrak Station. The journey, including transfers, takes approximately 29h 10m.
The distance between Charleston and Chicago is 773 miles. The road distance is 878.6 miles.
The best way to get from Charleston to Chicago without a car is to train which takes 29h 10m and costs $370 - $950.
It takes approximately 4h 15m to get from Charleston to Chicago, including transfers.
Charleston to Chicago bus services, operated by Greyhound USA, depart from Charleston Bus Station.
Charleston to Chicago train services, operated by Amtrak, depart from Charleston Amtrak Station.
The best way to get from Charleston to Chicago is to fly which takes 4h 15m and costs $85 - $460. Alternatively, you can train, which costs $370 - $950 and takes 29h 10m, you could also bus, which costs $170 - $320 and takes 31h 3m.
What companies run services between Charleston, SC, USA and Chicago, IL, USA?
Southwest Airlines and Delta fly from Charleston International Airport (CHS) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, you can take a vehicle from Charleston to Chicago Union Station via Charleston Amtrak Station and Petersburg Amtrak Station in around 29h 10m.
- Website
- southwest.com
Flights from Charleston International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $85–460
Flights from Charleston International Airport to Chicago Midway International Airport via Nashville
- Ave. Duration
- 4h 38m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $90–480
- Website
- delta.com
Flights from Charleston International Airport to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $90–480
Flights from Charleston International Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $70–390
- Website
- aa.com
Flights from Charleston International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $65–370
Flights from Charleston International Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $65–370
- Website
- united.com
Flights from Charleston International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- $65–370
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Petersburg Amtrak Station
- Ave. Duration
- 6h 16m
- Frequency
- Twice daily
- Estimated price
- $100–260
- Website
- Amtrak
Train from Petersburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 21h 41m
- Frequency
- Once daily
- Estimated price
- $240–650
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 35m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h
- Frequency
- 4 times a day
- Estimated price
- $110–190
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h 10m
- Frequency
- Twice daily
- Estimated price
- $100–170
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Charleston to Chicago bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Chicago is 1h behind Charleston. It is currently 11:23 PM in Charleston and 10:23 PM in Chicago.
Charleston to Chicago train services, operated by Amtrak, arrive at Petersburg Amtrak Station.
Yes, the driving distance between Charleston to Chicago is 879 miles. It takes approximately 15h 58m to drive from Charleston to Chicago.
Book your Charleston to Chicago train tickets online with Omio.
Book your Charleston to Chicago bus tickets online with Omio.
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