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How to get fromCharleston to Duke Universityby train (Amtrak), bus (Greyhound), car, plane, or train

Find Transport to Duke University

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There are 7 ways to get from Charleston to Duke University by train (Amtrak), bus (Greyhound), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Charleston Amtrak Station to Selma Stationtrain train Palmetto
    2. Take the train from Selma Station to Durham Amtrak Stationtrain train Carolinian
    7h 8m
    $184–289

  2. Drive  260.7 mi

    cheapest
    1. Drive from Charleston to Duke Universitycar car 260.7 mi
    5h 48m
    $47–67

  3. Bus (Greyhound)

    1. Take the bus from Charleston Bus Station to Raleigh Bus Stationbus bus Greyhound US0645S
    11h 55m
    $63–102

  4. Fly Charleston International Airport to Raleigh-Durham International Airport

    1. Fly from Charleston International Airport (CHS) to Raleigh-Durham International Airport (RDU)plane plane CHS - RDU
    6h 27m
    $277–486

  5. Fly Charleston International Airport to Piedmont Triad International Airport, train

    1. Fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO)plane plane CHS - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 22m
    $113–437

  6. Drive to Hilton Head Airport, fly to Raleigh-Durham International Airport

    1. Drive from Charleston to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Raleigh-Durham International Airport (RDU)plane plane HHH - RDU
    7h 58m
    $95–483

  7. Fly Charleston International Airport to Charlotte Douglas International Airport, train

    1. Fly from Charleston International Airport (CHS) to Charlotte Douglas International Airport (CLT)plane plane CHS - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    7h 44m
    $163–678

Charleston to Duke University by bus and foot (Greyhound)

Calendar7Weekly Services
Duration11h 55mAverage Duration
Ticket$63Cheapest Price
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Comparing Your Travel Options

Map of how to get from Charleston to Duke University.ExpandLaunch map view
  • Distance: 291.7 mi
  • Duration: 7h 8m

What companies run services between Charleston, SC, USA and Duke University, NC, USA?

You can take a vehicle from Charleston to Duke University via Charleston Amtrak Station, Selma Station, Durham Amtrak Station, Durham Station, and Trent Dr at Erwin Rd in around 7h 8m. Alternatively, Greyhound USA operates a bus from Charleston Bus Station to Raleigh Bus Station once daily. Tickets cost $55–90 and the journey takes 7h 15m.

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