There are 7 ways to get from Charleston to Frederick by plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Charleston International Airport to Baltimore-Washington International Airport, bus
best- Fly from Charleston International Airport (CHS) to Baltimore-Washington International Airport (BWI)plane CHS - BWI
- Take the bus from Baltimore Airport to Frederick Bus Stationbus
5h 3m$494–1,171Fly Charleston International Airport to Washington Dulles International Airport, subway, bus
cheapest- Fly from Charleston International Airport (CHS) to Washington Dulles International Airport (IAD)plane CHS - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
6h 16m$78–442Train
- Take the train from Charleston Amtrak Station to Washington Union Stationtrain Silver Meteor / ...
- Take the train from Washington Union Station to FREDERICK MARC wbtrain Marc
12h 45m$163–338Bus
- Take the bus from Charleston Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Frederick Bus Stationbus
17h 53m$101–170Drive 538 mi
- Drive from Charleston to Frederickcar 538 mi
10h 6m$99–142Fly Charleston International Airport to Ronald Reagan Washington National Airport, bus
- Fly from Charleston International Airport (CHS) to Ronald Reagan Washington National Airport (DCA)plane CHS - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
5h 35m$448–1,080Drive to Hilton Head Airport, fly to Ronald Reagan Washington National Airport, bus
- Drive from Charleston to Hilton Head Airport (HHH)car
- Fly from Hilton Head Airport (HHH) to Ronald Reagan Washington National Airport (DCA)plane HHH - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
6h 40m$115–586
Charleston to Frederick by bus
Comparing Your Travel Options
The cheapest way to get from Charleston to Frederick is to drive which costs $95 - $150 and takes 10h 6m.
The fastest way to get from Charleston to Frederick is to fly and bus which takes 5h 3m and costs $490 - $1,200.
No, there is no direct bus from Charleston to Frederick station. However, there are services departing from Mary St / Meeting St and arriving at Frederick Bus Station via N. Charleston SuperStop, Charleston Bus Station, Raleigh Bus Station and Washington Union Station. The journey, including transfers, takes approximately 17h 53m.
No, there is no direct train from Charleston station to Frederick. However, there are services departing from Charleston Amtrak Station and arriving at FREDERICK MARC wb via Washington Union Station. The journey, including transfers, takes approximately 12h 45m.
The distance between Charleston and Frederick is 539 miles. The road distance is 541.1 miles.
The best way to get from Charleston to Frederick without a car is to train which takes 12h 45m and costs $160 - $340.
It takes approximately 5h 3m to get from Charleston to Frederick, including transfers.
Charleston to Frederick bus services, operated by Greyhound USA, depart from Charleston Bus Station.
Charleston to Frederick train services, operated by Amtrak, depart from Charleston Amtrak Station.
The best way to get from Charleston to Frederick is to train which takes 12h 45m and costs $160 - $340. Alternatively, you can bus, which costs $100 - $170 and takes 17h 53m.
What companies run services between Charleston, SC, USA and Frederick, MD, USA?
You can take a vehicle from Charleston to FREDERICK MARC wb via Charleston Amtrak Station and Washington Union Station in around 12h 45m. Alternatively, you can take a bus from Mary St / Meeting St to Frederick Bus Station via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Raleigh Bus Station, and Washington Union Station in around 17h 53m.
- Website
- aa.com
Flights from Charleston International Airport to Baltimore-Washington International Airport via Charlotte
- Ave. Duration
- 3h 45m
- When
- Thursday and Sunday
- Estimated price
- $75–450
Flights from Charleston International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $95–600
Flights from Charleston International Airport to Ronald Reagan Washington National Airport via Charlotte
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $100–650
Flights from Charleston International Airport to Washington Dulles International Airport via Charlotte
- Ave. Duration
- 3h 37m
- When
- Thursday and Sunday
- Estimated price
- $75–450
Flights from Hilton Head Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $90–550
Flights from Hilton Head Airport to Ronald Reagan Washington National Airport via Charlotte
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $95–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Washington Union Station
- Ave. Duration
- 9h 51m
- Frequency
- Twice daily
- Estimated price
- $130–290
- Website
- Amtrak
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Baltimore Airport to Frederick Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
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Booking & Getting There
Charleston to Frederick bus services, operated by Greyhound USA, arrive at Raleigh Bus Station.
Charleston to Frederick train services, operated by Amtrak, arrive at Washington Union Station.
Yes, the driving distance between Charleston to Frederick is 541 miles. It takes approximately 10h 6m to drive from Charleston to Frederick.
Book your Charleston to Frederick train tickets online with Omio.
Book your Charleston to Frederick bus tickets online with Omio.
There are 65+ hotels available in Frederick.








