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How to get fromCharleston to Gainesvilleby plane, bus, train (Amtrak), car, train, or subway

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There are 6 ways to get from Charleston to Gainesville by plane, bus, train (Amtrak), car, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charleston International Airport to Ronald Reagan Washington National Airport, bus

    best
    1. Fly from Charleston International Airport (CHS) to Ronald Reagan Washington National Airport (DCA)plane plane CHS - DCA
    2. Take the bus from Wilson Blvd @ N Kent St to Heathcote Blvd @ Heritage Hunt Drbus bus
    5h 9m
    $447–1,084

  2. Drive 488.4 mi

    cheapest
    1. Drive from Charleston to Gainesvillecar car 488.4 mi
    9h 27m
    $90–129

  3. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Alexandriatrain train Palmetto / ...
    11h 31m
    $214–403

  4. Fly Charleston International Airport to Washington Dulles International Airport

    1. Fly from Charleston International Airport (CHS) to Washington Dulles International Airport (IAD)plane plane CHS - IAD
    5h 27m
    $601–1,087

  5. Bus to Charleston International Airport, fly to Baltimore-Washington International Airport, train, subway, bus

    1. Take the bus from Courtenay Dr / Doughty St to Fuel Farm Rd / Dreamliner Drbus bus
    2. Fly from Charleston International Airport (CHS) to Baltimore-Washington International Airport (BWI)plane plane CHS - BWI
    3. Take the train from BWI Thurgood Marshall to New Carrollton Amtrak Stationtrain train
    4. Take the subway from New Carrollton, Orange Line Center Platform to Virginia Square, Orange/Silver Line Track 2 Platformsubway subway
    5. Take the bus from N Fairfax Dr @ N Taylor St to Heathcote Blvd @ Heritage Hunt Drbus bus
    6h 19m

  6. Drive to Hilton Head Airport, fly to Ronald Reagan Washington National Airport, bus

    1. Drive from Charleston to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Ronald Reagan Washington National Airport (DCA)plane plane HHH - DCA
    3. Take the bus from Wilson Blvd @ N Kent St to Heathcote Blvd @ Heritage Hunt Drbus bus
    6h 13m
    $122–591

Charleston International Airport (CHS) to Ronald Reagan Washington National Airport (DCA) flights

Calendar45Weekly Planes
Duration2h 16mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Gainesville.ExpandLaunch map view
  • Distance: 493 mi
  • Duration: 5h 9m

What companies run services between Charleston, SC, USA and Gainesville, VA, USA?

Amtrak operates a train from Charleston Amtrak Station to Alexandria twice daily. Tickets cost $150–320 and the journey takes 9h 16m. Alternatively, United Airlines, American Airlines, and Delta fly from Charleston International Airport (CHS) to Washington Dulles International Airport (IAD) every 4 hours.

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