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How to get fromCharleston to Indianaby plane, bus (Greyhound), train (Amtrak), car, or train

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There are 8 ways to get from Charleston to Indiana by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Evansville

    best
    1. Fly from Charleston International Airport (CHS) to Evansville (EVV)plane plane CHS - EVV
    5h 14m
    $88–385

  2. Fly to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Charleston International Airport (CHS) to Chicago O'Hare International Airport (ORD)plane plane CHS - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 58m
    $75–339

  3. Bus

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    25h 43m
    $194–314

  4. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Alexandriatrain train Palmetto / ...
    2. Take the train from Alexandria to Indianapolistrain train Cardinal
    28h 25m
    $421–836

  5. Drive 694 mi

    1. Drive from Charleston to Indianapoliscar car 694 mi
    12h 47m
    $127–183

  6. Fly to Indianapolis

    1. Fly from Charleston International Airport (CHS) to Indianapolis (IND)plane plane CHS - IND
    6h 4m
    $102–522

  7. Fly to Chicago Midway International Airport, train

    1. Fly from Charleston International Airport (CHS) to Chicago Midway International Airport (MDW)plane plane CHS - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 26m
    $86–393

  8. Bus via Indianapolis, Illinois St (Greyhound Bus Station)

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus Greyhound US0100
    26h 43m
    $159–304

Charleston to Indiana by bus

Calendar7Weekly Buses
Duration25h 43mAverage Duration
Ticket$194Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Indiana.ExpandLaunch map view
  • Distance: 570.8 mi
  • Duration: 5h 14m

What companies run services between Charleston, SC, USA and Indiana, USA?

Delta and American Airlines fly from Charleston International Airport (CHS) to Evansville (EVV) every 4 hours. Alternatively, you can take a bus from Mary St / Meeting St to Indianapolis via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, and Atlanta Bus Station in around 25h 43m.

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