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How to get fromCharleston to Jeffersonvilleby plane, car, bus (Greyhound), train, or bus

Find Transport to Jeffersonville

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There are 5 ways to get from Charleston to Jeffersonville by plane, car, bus (Greyhound), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Blue Grass Airport, drive

    best
    1. Fly from Charleston International Airport (CHS) to Blue Grass Airport (LEX)plane plane CHS - LEX
    2. Drive from Lexington-Airport-LEX to Jeffersonvillecar car
    6h 8m
    $136–717

  2. Drive 581.3 mi

    cheapest
    1. Drive from Charleston to Jeffersonvillecar car 581.3 mi
    11h 18m
    $107–154

  3. Bus

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Cincinnati Bus Stationbus bus
    3. Take the bus from Greyhound Station Cincinnati to Louisville, KY Bus Stationbus bus
    28h 44m
    $155–332

  4. Train, bus (Amtrak)

    1. Take the train from Charleston Amtrak Station to Alexandriatrain train
    2. Take the train from Alexandria to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    32h 43m
    $424–884

  5. Fly to Louisville International Airport

    1. Fly from Charleston International Airport (CHS) to Louisville International Airport (SDF)plane plane CHS - SDF
    5h 33m
    $342–402

Charleston to Jeffersonville by bus and foot

Calendar14Weekly Services
Duration28h 44mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Jeffersonville.ExpandLaunch map view
  • Distance: 522.2 mi
  • Duration: 6h 8m

What companies run services between Charleston, SC, USA and Jeffersonville, IN, USA?

You can take a bus from Mary St / Meeting St to Court @ Meigs via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Atlanta Bus Station, Cincinnati Bus Station, Greyhound Station Cincinnati, Louisville, KY Bus Station, and Liberty @ Roy Wilkins in around 28h 44m. Alternatively, Breeze Airways, American Airlines, and three other airlines fly from Charleston International Airport (CHS) to Louisville International Airport (SDF) every 4 hours.

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