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How to get fromCharleston to Key Largoby plane, shuttle, train, bus, or car

Find Transport to Key Largo

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There are 4 ways to get from Charleston to Key Largo by plane, shuttle, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Miami International Airport, shuttle

    best
    1. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    5h 22m
    $599–1,114

  2. Drive  644.5 mi

    cheapest
    1. Drive from Charleston to Key Largocar car 644.5 mi
    10h 58m
    $118–170

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    17h 6m
    $212–439

  4. Fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    5h 45m
    $524–1,185

Charleston International Airport (CHS) to Miami International Airport (MIA) flights

Calendar60Weekly Planes
Duration3h 47mAverage Duration
Ticket$69Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Key Largo.ExpandLaunch map view
  • Distance: 558.8 mi
  • Duration: 5h 22m

What companies run services between Charleston, SC, USA and Key Largo, FL, USA?

There is no direct connection from Charleston to Key Largo. However, you can take the bus to Fuel Farm Rd / Dreamliner Dr, walk to Charleston-Airport-CHS airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, then take the shuttle to Key Largo, FL. Alternatively, you can take a vehicle from Charleston to Key Largo Bus Stop via Charleston Amtrak Station, Hollywood Amtrak Station, Hollywood Station, Miami, Airport Intermodal Station, and Miami Airport Station in around 17h 6m.

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