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How to get fromCharleston to Key Largoby plane, shuttle, train, bus, bus (Greyhound, Flixbus), or car

Find Transport to Key Largo

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There are 5 ways to get from Charleston to Key Largo by plane, shuttle, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Miami International Airport, shuttle

    best
    1. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    5h 18m
    $640–1,094

  2. Drive 644.5 mi

    cheapest
    1. Drive from Charleston to Key Largocar car 644.5 mi
    10h 58m
    $118–170

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    17h 6m
    $268–507

  4. Bus

    1. Take the bus from Charleston Bus Station to Savannah Bus Stationbus bus
    2. Take the bus from Savannah Bus Station to Ft Lauderdale Broward Park & Ridebus bus
    3. Take the bus from Ft Lauderdale Broward Park & Ride to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    19h 41m
    $124–213

  5. Fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    5h 49m
    $290–1,182

Charleston to Key Largo by bus

Calendar4Weekly Buses
Duration19h 41mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Key Largo.ExpandLaunch map view
  • Distance: 558.8 mi
  • Duration: 5h 18m

What companies run services between Charleston, SC, USA and Key Largo, FL, USA?

You can take a bus from Mary St / Meeting St to Key Largo Bus Stop via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Savannah Bus Station, Ft Lauderdale Broward Park & Ride, and Miami Airport Station in around 19h 41m.

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