There are 6 ways to get from Charleston to Lexington by plane, car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Charleston International Airport to Covington, drive
best- Fly from Charleston International Airport (CHS) to Covington (CVG)plane CHS - CVG
- Drive from Covington (CVG) to Lexingtoncar
4h 36m$128–687Fly Charleston International Airport to Blue Grass Airport
cheapest- Fly from Charleston International Airport (CHS) to Blue Grass Airport (LEX)plane CHS - LEX
7h 26m$69–397Train, bus, drive (Amtrak)
- Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain
- Take the bus from Chicago Union Station to Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
41h 24m$784–1,228Drive 514.5 mi
- Drive from Charleston to Lexingtoncar 514.5 mi
9h 39m$85–123Fly Charleston International Airport to Louisville International Airport, drive
- Fly from Charleston International Airport (CHS) to Louisville International Airport (SDF)plane CHS - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
4h 45m$134–716Drive to Hilton Head Airport, fly to Blue Grass Airport
- Drive from Charleston to Hilton Head Airport (HHH)car
- Fly from Hilton Head Airport (HHH) to Blue Grass Airport (LEX)plane HHH - LEX
8h 31m$79–386
Charleston International Airport (CHS) to Covington (CVG) flights
Comparing Your Travel Options
The cheapest way to get from Charleston to Lexington is to drive which costs $85 - $130 and takes 9h 39m.
The fastest way to get from Charleston to Lexington is to fly and drive which takes 4h 36m and costs $120 - $700.
The distance between Charleston and Lexington is 596 miles. The road distance is 517.5 miles.
It takes approximately 4h 36m to get from Charleston to Lexington, including transfers.
Yes, the driving distance between Charleston to Lexington is 517 miles. It takes approximately 9h 39m to drive from Charleston to Lexington.
There are 182+ hotels available in Lexington.
What companies run services between Charleston, SC, USA and Lexington, KY, USA?
American Airlines, Delta, and United Airlines fly from Charleston International Airport (CHS) to Blue Grass Airport (LEX) hourly.
- Website
- aa.com
Flights from Charleston International Airport to Covington via Charlotte
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $110–700
Flights from Charleston International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $120–700
Flights from Charleston International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 3h 49m
- When
- Thursday, Friday, Sunday, Monday, Tuesday, and Wednesday
- Estimated price
- $65–400
Flights from Charleston International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $100–550
Flights from Hilton Head Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $60–360
- Website
- delta.com
Flights from Charleston International Airport to Covington via Atlanta
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $130–750
Flights from Charleston International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $120–750
Flights from Charleston International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $70–420
Flights from Charleston International Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $110–600
Flights from Charleston International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 8h 12m
- When
- Every day
- Estimated price
- $100–500
Flights from Hilton Head Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $60–370
Flights from Hilton Head Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 7h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–500
- Website
- united.com
Flights from Charleston International Airport to Covington via Washington Dulles
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $150–800
Flights from Charleston International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $160–850
Flights from Charleston International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $100–550
Flights from Hilton Head Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $95–470
- Website
- flybreeze.com
Flights from Charleston International Airport to Covington
- Ave. Duration
- 1h 51m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $260–1,600
Flights from Charleston International Airport to Louisville International Airport
- Ave. Duration
- 1h 52m
- When
- Monday and Friday
- Estimated price
- $270–1,600
- Website
- allegiantair.com
Flights from Charleston International Airport to Covington
- Ave. Duration
- 1h 42m
- When
- Thursday and Sunday
- Estimated price
- $110–700
- Website
- southwest.com
Flights from Charleston International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Petersburg Amtrak Station
- Ave. Duration
- 6h 16m
- Frequency
- Twice daily
- Estimated price
- $200–310
- Website
- Amtrak
Train from Petersburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 21h 41m
- Frequency
- Once daily
- Estimated price
- $490–800
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
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