There are 5 ways to get from Charleston to Lexington by train, bus, train (Amtrak), car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Charleston Amtrak Station to Fayetteville Amtrak Stationtrain Palmetto / ...
- Take the bus from Fayetteville Bus Station to Lexington Davidson Co Trans Termbus Greyhound US0647S
9h 23m$72–149Drive 262.7 mi
cheapest- Drive from Charleston to Lexingtoncar 262.7 mi
4h 34m$48–70Train (Amtrak)
- Take the train from Charleston Amtrak Station to Selma Stationtrain Palmetto
- Take the train from Selma Station to High Pointtrain Carolinian
9h 25m$133–270Fly
- Fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO)plane CHS - GSO
7h 9m$340–1,301Bus
- Take the bus from Charleston Bus Station to Fayetteville Bus Stationbus Greyhound US0645S
- Take the bus from Fayetteville Bus Station to Lexington Davidson Co Trans Termbus Greyhound US0647S
12h 53m$62–114
Charleston to Lexington by bus and train
Questions & Answers
The cheapest way to get from Charleston to Lexington is to drive which costs $45 - $70 and takes 4h 34m.
The fastest way to get from Charleston to Lexington is to drive which takes 4h 34m and costs $45 - $70.
No, there is no direct bus from Charleston to Lexington. However, there are services departing from Mary St / Meeting St and arriving at Lexington Davidson Co Trans Term via N. Charleston SuperStop, Charleston Bus Station and Fayetteville Bus Station. The journey, including transfers, takes approximately 12h 53m.
No, there is no direct train from Charleston station to Lexington. However, there are services departing from Charleston Amtrak Station and arriving at High Point via Selma Station. The journey, including transfers, takes approximately 9h 25m.
The distance between Charleston and Lexington is 304 miles. The road distance is 264.2 miles.
The best way to get from Charleston to Lexington without a car is to train and bus which takes 9h 23m and costs $70 - $150.
It takes approximately 9h 23m to get from Charleston to Lexington, including transfers.
Charleston to Lexington bus services, operated by Greyhound USA, depart from Charleston Bus Station.
Charleston to Lexington train services, operated by Amtrak, depart from Charleston Amtrak Station.
The best way to get from Charleston to Lexington is to train which takes 9h 25m and costs $130 - $270. Alternatively, you can fly, which costs $340 - $1,300 and takes 7h 9m, you could also bus, which costs $60 - $120 and takes 12h 53m.
What companies run services between Charleston, SC, USA and Lexington, NC, USA?
You can take a vehicle from Charleston to Lexington Davidson Co Trans Term via Charleston Amtrak Station, Selma Station, High Point, and High Point Transportation Terminal in around 9h 25m. Alternatively, American Airlines, Delta, and United Airlines fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO) hourly.
- Website
- aa.com
Flights from Charleston International Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $75–550
Flights from Charleston International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $150–800
Flights from Charleston International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
- Website
- delta.com
Flights from Charleston International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Charleston International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $120–700
Flights from Charleston International Airport to Piedmont Triad International Airport via Newark
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $50–120
- Website
- Amtrak
Train from Charleston Amtrak Station to Selma Station
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- Amtrak
Train from Selma Station to High Point
- Ave. Duration
- 2h 53m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Fayetteville Bus Station to Lexington Davidson Co Trans Term
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Greyhound
Bus from Charleston Bus Station to Fayetteville Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Fayetteville Bus Station to Lexington Davidson Co Trans Term
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Greyhound
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Fayetteville Bus Station to Lexington Davidson Co Trans Term
- Ave. Duration
- 3h 1m
- Frequency
- Once daily
- Estimated price
- $18–25
- Schedules at
- sunwaycharters.com
- Passenger
- $18–25
Bus from Fayetteville Bus Station to Lexington Davidson Co Trans Term
- Ave. Duration
- 3h 1m
- Frequency
- Once daily
- Estimated price
- $18–25
- Schedules at
- sunwaycharters.com
- Passenger
- $18–25
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More Questions & Answers
Charleston to Lexington bus services, operated by Greyhound USA, arrive at Fayetteville Bus Station.
Charleston to Lexington train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Charleston to Lexington is 264 miles. It takes approximately 4h 34m to drive from Charleston to Lexington.
Book your Charleston to Lexington bus tickets online with Omio.
There are 39+ hotels available in Lexington.





