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How to get fromCharleston to Mayoby train, bus, taxi, car, or plane

Find Transport to Mayo

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There are 4 ways to get from Charleston to Mayo by train, bus, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus, taxi

    best
    1. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    3. Take the taxi from Lake City Bus Station to Mayotaxi taxi
    8h 27m
    $246–386

  2. Drive 319.7 mi

    cheapest
    1. Drive from Charleston to Mayocar car 319.7 mi
    6h 27m
    $59–85

  3. Fly to Valdosta, drive

    1. Fly from Charleston International Airport (CHS) to Valdosta (VLD)plane plane CHS - VLD
    2. Drive from Valdosta (VLD) to Mayocar car
    6h 25m
    $71–363

  4. Fly to Tallahassee, bus, taxi

    1. Fly from Charleston International Airport (CHS) to Tallahassee (TLH)plane plane CHS - TLH
    2. Take the bus from Tallahassee to Perrybus bus
    3. Take the taxi from Perry to Mayotaxi taxi
    7h 40m
    $199–606

Charleston International Airport (CHS) to Valdosta (VLD) flights

Calendar15Weekly Planes
Duration4h 5mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Mayo.ExpandLaunch map view
  • Distance: 365.2 mi
  • Duration: 8h 27m

What companies run services between Charleston, SC, USA and Mayo, FL, USA?

There is no direct connection from Charleston to Mayo. However, you can take the taxi to Charleston Amtrak Station, take the train to Jacksonville, walk to Amtrak Station, take the line 4 bus to JRTC Bay H, walk to Jacksonville, take the bus to Lake City Bus Station, then take the taxi to Mayo. Alternatively, you can drive from Charleston to Mayo in around 6h 27m.

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