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How to get fromCharleston to Mechanicsburgby plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 5 ways to get from Charleston to Mechanicsburg by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport

    best
    1. Fly from Charleston International Airport (CHS) to Harrisburg International Airport (MDT)plane plane CHS - MDT
    6h 42m
    $66–355

  2. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to 30th Street Stationtrain train Palmetto / ...
    2. Take the train from 30th Street Station to Harrisburgtrain train Keystone Service / ...
    16h 43m
    $262–528

  3. Bus

    1. Take the bus from Charleston Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    20h 51m
    $111–213

  4. Drive 601.8 mi

    1. Drive from Charleston to Mechanicsburgcar car 601.8 mi
    11h 26m
    $110–159

  5. Fly to Philadelphia International Airport, train

    1. Fly from Charleston International Airport (CHS) to Philadelphia International Airport (PHL)plane plane CHS - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    7h 53m
    $369–940

Charleston to Mechanicsburg by bus and foot

Calendar14Weekly Services
Duration20h 51mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Mechanicsburg.ExpandLaunch map view
  • Distance: 567.6 mi
  • Duration: 6h 42m

What companies run services between Charleston, SC, USA and Mechanicsburg, Cumberland County, PA, USA?

United Airlines, American Airlines, and Delta fly from Charleston International Airport (CHS) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a vehicle from Charleston to E Main St & Arch St WB via Charleston Amtrak Station, 30th Street Station, Harrisburg, and Market Square Transfer Center in around 16h 43m.

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