There are 4 ways to get from Charleston to Memphis by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Charleston International Airport
best- Fly from Charleston International Airport (CHS) to Memphis (MEM)plane CHS - MEM
6h 25m$151–837Drive 665.2 mi
cheapest- Drive from Charleston to Memphiscar 665.2 mi
11h 50m$114–165Bus (Greyhound)
- Take the bus from Charleston Bus Station to Atlanta Bus Stationbus Greyhound US0641S
- Take the bus from Atlanta Bus Station to Memphis Bus Stationbus Greyhound US0610
24h 16m$155–245Drive to Hilton Head Airport, fly
- Drive from Charleston to Hilton Head Airport (HHH)car
- Fly from Hilton Head Airport (HHH) to Memphis (MEM)plane HHH - MEM
8h 10m$149–776
Charleston to Memphis by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Charleston to Memphis is to drive which costs $110 - $170 and takes 11h 50m.
The fastest way to get from Charleston to Memphis is to fly which takes 6h 25m and costs $150 - $850.
No, there is no direct bus from Charleston to Memphis. However, there are services departing from Mary St / Meeting St and arriving at 3RD STREET at EXCHANGE AVENUE via N. Charleston SuperStop, Charleston Bus Station, Atlanta Bus Station and Airways Transit Center. The journey, including transfers, takes approximately 24h 16m.
The distance between Charleston and Memphis is 617 miles. The road distance is 669.1 miles.
The best way to get from Charleston to Memphis without a car is to bus which takes 24h 16m and costs $150 - $250.
It takes approximately 6h 25m to get from Charleston to Memphis, including transfers.
Charleston to Memphis bus services, operated by Greyhound USA, depart from Charleston Bus Station.
The best way to get from Charleston to Memphis is to fly which takes 6h 25m and costs $150 - $850. Alternatively, you can bus, which costs $150 - $250 and takes 24h 16m.
Charleston to Memphis bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Memphis is 1h behind Charleston. It is currently 11:13 PM in Charleston and 10:13 PM in Memphis.
What companies run services between Charleston, SC, USA and Memphis, TN, USA?
Delta, Southwest Airlines, and American Airlines fly from Charleston International Airport (CHS) to Memphis (MEM) hourly. Alternatively, you can take a bus from Mary St / Meeting St to 3RD STREET at EXCHANGE AVENUE via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Atlanta Bus Station, and Airways Transit Center in around 24h 16m.
- Website
- delta.com
Flights from Charleston International Airport to Memphis via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $150–850
Flights from Hilton Head Airport to Memphis via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $130–750
Flights from Hilton Head Airport to Memphis via New York La Guardia
- Ave. Duration
- 6h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,200
- Website
- aa.com
Flights from Charleston International Airport to Memphis via Charlotte
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $160–900
Flights from Hilton Head Airport to Memphis via Charlotte
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $140–800
Flights from Hilton Head Airport to Memphis via Reagan Washington
- Ave. Duration
- 7h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $200–1,000
- Website
- southwest.com
Flights from Charleston International Airport to Memphis via Nashville
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $150–900
Flights from Charleston International Airport to Memphis via Chicago Midway
- Ave. Duration
- 4h 55m
- When
- Tuesday and Wednesday
- Estimated price
- $230–1,100
Flights from Charleston International Airport to Memphis via Baltimore
- Ave. Duration
- 5h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,100
Flights from Charleston International Airport to Memphis via Houston Hobby Apt
- Ave. Duration
- 6h 45m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,200
- Website
- united.com
Flights from Hilton Head Airport to Memphis via Chicago O'Hare
- Ave. Duration
- 9h 39m
- When
- Every day
- Estimated price
- $200–1,000
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 35m
- Frequency
- Once daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Atlanta Bus Station to Memphis Bus Station
- Ave. Duration
- 7h 55m
- Frequency
- Twice daily
- Estimated price
- $65–110
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between Charleston to Memphis is 669 miles. It takes approximately 11h 50m to drive from Charleston to Memphis.
Book your Charleston to Memphis bus tickets online with Omio.
There are 430+ hotels available in Memphis.


