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How to get fromCharleston to Mobileby plane, bus (Greyhound), car, bus, or train

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There are 8 ways to get from Charleston to Mobile by plane, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charleston International Airport to Mobile Regional Airport

    best
    1. Fly from Charleston International Airport (CHS) to Mobile Regional Airport (MOB)plane plane CHS - MOB
    7h 45m
    $65–360

  2. Bus

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Mobile Bus Stationbus bus Greyhound US0602 / ...
    22h 19m
    $154–264

  3. Drive 578.7 mi

    1. Drive from Charleston to Mobilecar car 578.7 mi
    10h 48m
    $106–153

  4. Fly Charleston International Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Charleston International Airport (CHS) to Destin–Fort Walton Beach Airport (VPS)plane plane CHS - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    6h 44m
    $83–374

  5. Fly Charleston International Airport to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Charleston International Airport (CHS) to Gulfport-Biloxi Regional Airport (GPT)plane plane CHS - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 25m
    $144–508

  6. Fly Charleston International Airport to Pensacola International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Pensacola International Airport (PNS)plane plane CHS - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 23m
    $376–1,176

  7. Drive to Hilton Head Airport, fly to Mobile Regional Airport

    1. Drive from Charleston to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Mobile Regional Airport (MOB)plane plane HHH - MOB
    9h 38m
    $84–377

  8. Fly Charleston International Airport to Louis Armstrong New Orleans International Airport, train

    1. Fly from Charleston International Airport (CHS) to Louis Armstrong New Orleans International Airport (MSY)plane plane CHS - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    8h 28m
    $147–592

Charleston to Mobile by bus

Calendar7Weekly Buses
Duration22h 19mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Mobile.ExpandLaunch map view
  • Distance: 540.3 mi
  • Duration: 7h 45m

What companies run services between Charleston, SC, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Charleston International Airport (CHS) to Mobile Regional Airport (MOB) every 3 hours. Alternatively, you can take a bus from Mary St / Meeting St to Govt EB Mid Block Past Joachim St via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Atlanta Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 22h 19m.

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