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How to get fromCharleston to Sanibel Islandby plane, train, bus, taxi, or car

Find Transport to Sanibel Island

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There are 6 ways to get from Charleston to Sanibel Island by plane, train, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Charleston International Airport (CHS) to Ft. Myers (RSW)plane plane CHS - RSW
    3h 38m
    $164–547

  2. Drive 547.9 mi

    cheapest
    1. Drive from Charleston to Sanibel Islandcar car 547.9 mi
    10h 4m
    $100–145

  3. Train, bus via Jacksonville

    1. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    2. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    3. Take the bus from Wildwood to Fort Myersbus bus
    17h 52m
    $244–394

  4. Train, bus, taxi

    1. Take the train from Charleston Amtrak Station to Fort Lauderdale Amtrak Stationtrain train
    2. Take the bus from Fort Lauderdale Airport to Naples, FLbus bus
    3. Take the taxi from Naples, FL to Sanibel Islandtaxi taxi
    17h 55m
    $387–681

  5. Train, bus (Amtrak)

    1. Take the train from Charleston Amtrak Station to Orlandotrain train Silver Meteor
    2. Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus bus Amtrak Thruway Connecting Service
    17h 56m
    $264–464

  6. Train, bus #2

    1. Take the train from Charleston Amtrak Station to Kissimmee Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Orlando to Fort Myers Bus Stopbus bus FlixBus 2421
    20h 44m
    $217–404

Charleston International Airport (CHS) to Ft. Myers (RSW) flights

Calendar23Weekly Planes
Duration3h 2mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Sanibel Island.ExpandLaunch map view
  • Distance: 486.5 mi
  • Duration: 3h 38m

What companies run services between Charleston, SC, USA and Sanibel Island, FL, USA?

Breeze Airways, Delta, and American Airlines fly from Charleston International Airport (CHS) to Ft. Myers (RSW) 3 times a day.

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