What is the cheapest way to get from Charleston to St. Louis?

The cheapest way to get from Charleston to St. Louis is to drive which costs $150 - $230 and takes 14h 43m.

What is the fastest way to get from Charleston to St. Louis?

The fastest way to get from Charleston to St. Louis is to fly which takes 4h 6m and costs $110 - $600.

Is there a direct bus between Charleston and St. Louis?

No, there is no direct bus from Charleston to St. Louis station. However, there are services departing from Mary St / Meeting St and arriving at St Louis Bus Station via N. Charleston SuperStop, Charleston Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 25h 43m.

How far is it from Charleston to St. Louis?

The distance between Charleston and St. Louis is 735 miles. The road distance is 845.9 miles.

How do I travel from Charleston to St. Louis without a car?

The best way to get from Charleston to St. Louis without a car is to bus which takes 25h 43m and costs $150 - $320.

How long does it take to get from Charleston to St. Louis?

It takes approximately 4h 6m to get from Charleston to St. Louis, including transfers.

Where do I catch the Charleston to St. Louis bus from?

Charleston to St. Louis bus services, operated by Greyhound USA, depart from Charleston Bus Station.

Bus or fly from Charleston to St. Louis?

The best way to get from Charleston to St. Louis is to fly which takes 4h 6m and costs $110 - $600. Alternatively, you can bus, which costs $150 - $320 and takes 25h 43m.

Where does the Charleston to St. Louis bus arrive?

Charleston to St. Louis bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.

What is the time difference between Charleston and St. Louis?

St. Louis is 1h behind Charleston. It is currently 12:07 PM in Charleston and 11:07 AM in St. Louis.

Can I drive from Charleston to St. Louis?

Yes, the driving distance between Charleston to St. Louis is 846 miles. It takes approximately 14h 43m to drive from Charleston to St. Louis.

How do I get a bus ticket from Charleston to St. Louis?

Book your Charleston to St. Louis bus tickets online with Omio.

Where can I stay near St. Louis?

There are 485+ hotels available in St. Louis.

Charleston to St. Louis - 4 ways to travel via plane, bus, and car

How to get fromCharleston to St. Louis

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There are 4 ways to get from Charleston to St. Louis by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Charleston International Airport
best
1. Fly from Charleston International Airport (CHS) to Lambert–St. Louis International Airport (STL)plane CHS - STL
4h 6m
$116–566
Bus
1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus Greyhound US0641S
2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus FlixBus N2521
25h 43m
$159–314
Drive 841 mi
1. Drive from Charleston to St. Louiscar 841 mi
14h 43m
$154–222
Drive to Hilton Head Airport, fly
1. Drive from Charleston to Hilton Head Airport (HHH)car
2. Fly from Hilton Head Airport (HHH) to Lambert–St. Louis International Airport (STL)plane HHH - STL
8h
$132–630

Charleston to St. Louis by bus

7Weekly Buses

25h 43mAverage Duration

$159Cheapest Price

See schedules

Questions & Answers

Map of how to get from Charleston to St. Louis.

Launch map view

Distance: 731.1 mi
Duration: 4h 6m

What companies run services between Charleston, SC, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and American Airlines fly from Charleston International Airport (CHS) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Mary St / Meeting St to St Louis Bus Station via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, and Atlanta Bus Station in around 25h 43m.

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Bus operators

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How to get fromCharleston to St. Louisby plane, bus (Greyhound, Flixbus), or car

There are 4 ways to get from Charleston to St. Louis by plane, bus (Greyhound, Flixbus), or car

Fly from Charleston International Airport

Bus

Drive 841 mi

Drive to Hilton Head Airport, fly