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How to get fromCharleston to Tupeloby plane, car, or bus (Greyhound)

Find Transport to Tupelo

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There are 5 ways to get from Charleston to Tupelo by plane, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Charleston International Airport (CHS) to Golden Triangle Regional Airport (GTR)plane plane CHS - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    6h 34m
    $80–416

  2. Bus (Greyhound)

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    21h 2m
    $150–228

  3. Drive  563.4 mi

    1. Drive from Charleston to Tupelocar car 563.4 mi
    10h 10m
    $100–144

  4. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Charleston International Airport (CHS) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane CHS - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    7h 14m
    $85–417

  5. Fly to Tupelo Regional Airport

    1. Fly from Charleston International Airport (CHS) to Tupelo Regional Airport (TUP)plane plane CHS - TUP
    7h 40m
    $113–564

Charleston International Airport (CHS) to Golden Triangle Regional Airport (GTR) flights

Calendar9Weekly Planes
Duration4h 6mAverage Duration
Ticket$69Cheapest Price
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Comparing Your Travel Options

Map of how to get from Charleston to Tupelo.ExpandLaunch map view
  • Distance: 569.6 mi
  • Duration: 6h 34m

What companies run services between Charleston, SC, USA and Tupelo, MS, USA?

You can take a bus from Mary St / Meeting St to Tupelo via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Atlanta Bus Station, and Tupelo in around 21h 2m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from Charleston International Airport (CHS) to Tupelo Regional Airport (TUP) twice daily.

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