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How to get fromCharleston to Tupeloby plane, car, train, bus, bus (Greyhound, Flixbus), or bus (Greyhound)

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There are 7 ways to get from Charleston to Tupelo by plane, car, train, bus, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Charleston International Airport (CHS) to Golden Triangle Regional Airport (GTR)plane plane CHS - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    6h 35m
    $74–361

  2. Train, bus

    1. Take the train from Charleston Amtrak Station to Savannah Stationtrain train
    2. Take the bus from Savannah to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Tupelobus bus
    14h 11m

  3. Drive 563.4 mi

    1. Drive from Charleston to Tupelocar car 563.4 mi
    10h 10m
    $103–149

  4. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Charleston International Airport (CHS) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane CHS - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    6h 59m
    $298–645

  5. Fly to Tupelo Regional Airport

    1. Fly from Charleston International Airport (CHS) to Tupelo Regional Airport (TUP)plane plane CHS - TUP
    7h 39m
    $88–398

  6. Bus via Savannah

    1. Take the bus from Charleston Bus Station to Savannah Bus Stationbus bus
    2. Take the bus from Savannah Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tupelobus bus
    16h 53m
    $107–213

  7. Bus

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    20h 52m
    $125–243

Charleston International Airport (CHS) to Golden Triangle Regional Airport (GTR) flights

Calendar14Weekly Planes
Duration4h 10mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Tupelo.ExpandLaunch map view
  • Distance: 569.6 mi
  • Duration: 6h 35m

What companies run services between Charleston, SC, USA and Tupelo, MS, USA?

Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from Charleston International Airport (CHS) to Tupelo Regional Airport (TUP) twice daily. Alternatively, you can take a bus from Mary St / Meeting St to Tupelo via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Savannah Bus Station, Atlanta Bus Station, and Tupelo in around 16h 53m.

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