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How to get fromCharleston to West Lafayetteby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

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There are 8 ways to get from Charleston to West Lafayette by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Purdue University Airport

    best
    1. Fly from Charleston International Airport (CHS) to Purdue University Airport (LAF)plane plane CHS - LAF
    9h 4m
    $89–422

  2. Fly to Chicago O'Hare International Airport, bus

    cheapest
    1. Fly from Charleston International Airport (CHS) to Chicago O'Hare International Airport (ORD)plane plane CHS - ORD
    2. Take the bus from Chicago Bus Station to Lafayette Bus Stopbus bus
    7h 50m
    $85–365

  3. Bus

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Lafayette Bus Stopbus bus Greyhound US0100
    29h 8m
    $164–324

  4. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Alexandriatrain train Palmetto / ...
    2. Take the train from Alexandria to Lafayette Amtrak Stationtrain train Cardinal
    30h 31m
    $431–916

  5. Drive 757.7 mi

    1. Drive from Charleston to West Lafayettecar car 757.7 mi
    14h 1m
    $139–200

  6. Fly to Indianapolis, bus

    1. Fly from Charleston International Airport (CHS) to Indianapolis (IND)plane plane CHS - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 12m
    $127–565

  7. Fly to Chicago Midway International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Chicago Midway International Airport (MDW)plane plane CHS - MDW
    2. Take the bus from Chicago Bus Station to Lafayette Bus Stopbus bus
    7h 29m
    $99–422

  8. Bus via Bloomington

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Bloomingtonbus bus
    3. Take the bus from Bloomington to Lafayette Bus Stopbus bus
    29h 8m
    $172–314

Charleston to West Lafayette by bus

Calendar14Weekly Buses
Duration29h 8mAverage Duration
Ticket$164Cheapest Price
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Questions & Answers

Map of how to get from Charleston to West Lafayette.ExpandLaunch map view
  • Distance: 658.6 mi
  • Duration: 9h 4m

What companies run services between Charleston, SC, USA and West Lafayette, IN, USA?

United Airlines, American Airlines, and Breeze Airways fly from Charleston International Airport (CHS) to Purdue University Airport (LAF) every 4 hours. Alternatively, you can take a bus from Mary St / Meeting St to Lafayette Bus Stop via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, and Atlanta Bus Station in around 29h 8m.

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