There are 6 ways to get from Charleston to Winston-Salem, NC by plane, train (Amtrak), train, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Piedmont Triad International Airport
best- Fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO)plane CHS - GSO
4h 54m$374–1,344Drive 281.6 mi
cheapest- Drive from Charleston to Winston-Salem, NCcar 281.6 mi
4h 52m$52–75Train (Amtrak)
- Take the train from Charleston Amtrak Station to Selma Stationtrain Palmetto
- Take the train from Selma Station to High Pointtrain Carolinian
8h 23m$181–326Train, bus
- Take the train from Charleston Amtrak Station to Fayetteville Amtrak Stationtrain Palmetto / ...
- Take the bus from Fayetteville to Winston-Salembus Winston-Salem to Fayetteville
10h 3m$89–180Fly to Charlotte Douglas International Airport, bus
- Fly from Charleston International Airport (CHS) to Charlotte Douglas International Airport (CLT)plane CHS - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 46m$77–475Bus
- Take the bus from Charleston Bus Station to Charlotte Bus Stationbus Greyhound US0643S
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus Greyhound US0670
11h 48m$59–140
Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO) flights
Questions & Answers
The cheapest way to get from Charleston to Winston-Salem, NC is to drive which costs $50 - $75 and takes 4h 52m.
The fastest way to get from Charleston to Winston-Salem, NC is to drive which takes 4h 52m and costs $50 - $75.
No, there is no direct bus from Charleston to Winston-Salem, NC. However, there are services departing from Mary St / Meeting St and arriving at Winston Salem(Trans Center) via N. Charleston SuperStop, Charleston Bus Station and Charlotte Bus Station. The journey, including transfers, takes approximately 11h 48m.
No, there is no direct train from Charleston station to Winston-Salem, NC. However, there are services departing from Charleston Amtrak Station and arriving at High Point via Selma Station. The journey, including transfers, takes approximately 8h 23m.
The distance between Charleston and Winston-Salem, NC is 259 miles. The road distance is 283.2 miles.
The best way to get from Charleston to Winston-Salem, NC without a car is to train which takes 8h 23m and costs $180 - $330.
It takes approximately 4h 54m to get from Charleston to Winston-Salem, NC, including transfers.
Charleston to Winston-Salem, NC bus services, operated by Greyhound USA, depart from Charleston Bus Station.
Charleston to Winston-Salem, NC train services, operated by Amtrak, depart from Charleston Amtrak Station.
The best way to get from Charleston to Winston-Salem, NC is to fly which takes 4h 54m and costs $370 - $1,400. Alternatively, you can train, which costs $180 - $330 and takes 8h 23m, you could also bus, which costs $55 - $140 and takes 11h 48m.
What companies run services between Charleston, SC, USA and Winston-Salem, NC, USA?
American Airlines, Delta, and United Airlines fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a vehicle from Charleston to Winston-Salem, NC via Charleston Amtrak Station, Selma Station, and High Point in around 8h 23m.
- Website
- aa.com
Flights from Charleston International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $75–550
Flights from Charleston International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Charleston International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
Flights from Charleston International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $55–420
- Website
- delta.com
Flights from Charleston International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Charleston International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $120–700
Flights from Charleston International Airport to Piedmont Triad International Airport via Newark
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Selma Station
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- $70–150
- Website
- Amtrak
Train from Selma Station to High Point
- Ave. Duration
- 2h 53m
- Frequency
- Once daily
- Estimated price
- $35–85
- Website
- Amtrak
Train from Charleston Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- Amtrak
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- sunwaycharters.com
- Passenger
- $23–35
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Charleston Bus Station to Charlotte Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $11–22
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- Barons Bus
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- Barons Bus
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More Questions & Answers
Charleston to Winston-Salem, NC bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Charleston to Winston-Salem, NC train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Charleston to Winston-Salem, NC is 283 miles. It takes approximately 4h 52m to drive from Charleston to Winston-Salem, NC.
There are 136+ hotels available in Winston-Salem, NC.









