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How to get fromCharleston to Winston-Salem, NCby plane, train (Amtrak), train, bus, car, or bus (Greyhound)

Find Transport to Winston-Salem, NC

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There are 6 ways to get from Charleston to Winston-Salem, NC by plane, train (Amtrak), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO)plane plane CHS - GSO
    4h 54m
    $374–1,344
  2. Drive 281.6 mi

    cheapest
    1. Drive from Charleston to Winston-Salem, NCcar car 281.6 mi
    4h 52m
    $52–75
  3. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Selma Stationtrain train Palmetto
    2. Take the train from Selma Station to High Pointtrain train Carolinian
    8h 23m
    $181–326
  4. Train, bus

    1. Take the train from Charleston Amtrak Station to Fayetteville Amtrak Stationtrain train Palmetto / ...
    2. Take the bus from Fayetteville to Winston-Salembus bus Winston-Salem to Fayetteville
    10h 3m
    $89–180
  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Charlotte Douglas International Airport (CLT)plane plane CHS - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 46m
    $77–475
  6. Bus

    1. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus Greyhound US0643S
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    11h 48m
    $59–140

Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO) flights

Calendar104Weekly Planes
Duration4h 10mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

What companies run services between Charleston, SC, USA and Winston-Salem, NC, USA?

American Airlines, Delta, and United Airlines fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a vehicle from Charleston to Winston-Salem, NC via Charleston Amtrak Station, Selma Station, and High Point in around 8h 23m.

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