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How to get fromCharleston to Wythevilleby plane, bus, train, car, or bus (Greyhound)

Find Transport to Wytheville

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There are 7 ways to get from Charleston to Wytheville by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charleston International Airport to Charlotte Douglas International Airport, bus

    best
    1. Fly from Charleston International Airport (CHS) to Charlotte Douglas International Airport (CLT)plane plane CHS - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    6h 31m
    $118–501

  2. Drive 343.2 mi

    cheapest
    1. Drive from Charleston to Wythevillecar car 343.2 mi
    5h 50m
    $63–91

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Selma Stationtrain train
    2. Take the train from Selma Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Wythevillebus bus
    11h 41m
    $170–337

  4. Train, bus via Fayetteville

    1. Take the train from Charleston Amtrak Station to Fayetteville Amtrak Stationtrain train
    2. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Wythevillebus bus
    13h 8m
    $112–227

  5. Fly Charleston International Airport to Roanoke Regional Airport-Woodrum Field, bus

    1. Fly from Charleston International Airport (CHS) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane CHS - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Christiansburg to Wytheville Rural King Parking Lotbus bus
    8h 44m
    $72–334

  6. Drive to Hilton Head Airport, fly to Charlotte Douglas International Airport, bus

    1. Drive from Charleston to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Charlotte Douglas International Airport (CLT)plane plane HHH - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 37m
    $138–548

  7. Bus

    1. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus Greyhound US0643S
    2. Take the bus from Charlotte Bus Station to Wythevillebus bus Charlotte
    13h 13m
    $82–172

Charleston International Airport (CHS) to Charlotte Douglas International Airport (CLT) flights

Calendar50Weekly Planes
Duration1h 12mAverage Duration
Ticket$58Cheapest Price
See schedules

Questions & Answers

Map of how to get from Charleston to Wytheville.ExpandLaunch map view
  • Distance: 335.8 mi
  • Duration: 6h 31m

What companies run services between Charleston, SC, USA and Wytheville, VA, USA?

You can take a bus from Mary St / Meeting St to Wytheville via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Charlotte Bus Station, and Wytheville in around 13h 13m.

Airlines
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