There are 5 ways to get from Charleston to Florence by plane, bus (Greyhound), train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Yeager Airport (CRW) to Florence Regional Airport (FLO)plane CRW - FLO
3h 58m$83–438Bus
cheapest- Take the bus from Charleston, WV to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
9h 45m$58–112Train (Amtrak)
- Take the train from Charleston Station to Alexandriatrain Cardinal
- Take the train from Alexandria to Florence Stationtrain Palmetto / ...
18h 25m$236–503Drive 365 mi
- Drive from Charleston to Florencecar 365 mi
6h 47m$67–97Bus, train
- Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston-Salem to Fayettevillebus
- Take the train from Fayetteville Amtrak Station to Florence Stationtrain
12h 11m$81–166
Charleston to Florence by bus
Questions & Answers
The cheapest way to get from Charleston to Florence is to bus which costs $55 - $120 and takes 9h 45m.
The fastest way to get from Charleston to Florence is to fly which takes 3h 58m and costs $80 - $440.
No, there is no direct bus from Charleston to Florence station. However, there are services departing from Charleston, WV and arriving at Florence Bus Station via Charlotte Bus Station and Camden. The journey, including transfers, takes approximately 9h 45m.
No, there is no direct train from Charleston station to Florence station. However, there are services departing from Charleston Station and arriving at Florence Station via Alexandria. The journey, including transfers, takes approximately 18h 25m.
The distance between Charleston and Florence is 315 miles. The road distance is 367.1 miles.
The best way to get from Charleston to Florence without a car is to bus which takes 9h 45m and costs $55 - $120.
It takes approximately 3h 58m to get from Charleston to Florence, including transfers.
Charleston to Florence bus services, operated by Barons Bus, depart from Charleston, WV station.
Charleston to Florence train services, operated by Amtrak, depart from Charleston Station.
The best way to get from Charleston to Florence is to fly which takes 3h 58m and costs $80 - $440. Alternatively, you can bus, which costs $55 - $120 and takes 9h 45m, you could also train, which costs $230 - $550 and takes 18h 25m.
What companies run services between Charleston, WV, USA and Florence, SC, USA?
American Airlines flies from Yeager Airport (CRW) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Charleston, WV to Florence Bus Station via Charlotte Bus Station and Camden in around 9h 45m.
- Website
- aa.com
Flights from Yeager Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $60–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Station to Alexandria
- Ave. Duration
- 9h 56m
- Frequency
- 3 times a week
- Estimated price
- $110–250
- Website
- Amtrak
Train from Alexandria to Florence Station
- Ave. Duration
- 7h 29m
- Frequency
- Twice daily
- Estimated price
- $120–260
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Florence Station
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $26–70
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- Greyhound
Bus from Charleston Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Winston-Salem to Fayetteville
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- Greyhound
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Winston-Salem to Fayetteville
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- sunwaycharters.com
- Passenger
- $23–35
Want to know more about travelling around United States
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More Questions & Answers
Charleston to Florence bus services, operated by Barons Bus, arrive at Charlotte Bus Station.
Charleston to Florence train services, operated by Amtrak, arrive at Alexandria station.
Yes, the driving distance between Charleston to Florence is 367 miles. It takes approximately 6h 47m to drive from Charleston to Florence.
Book your Charleston to Florence train tickets online with Omio.
Book your Charleston to Florence bus tickets online with Omio and FlixBus.
There are 45+ hotels available in Florence.









