There are 4 ways to get from Charleston to Knoxville by plane, bus, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Yeager Airport (CRW) to Mcghee Tyson Airport (TYS)plane CRW - TYS
4h 2m$198–935Drive 308.2 mi
cheapest- Drive from Charleston to Knoxvillecar 308.2 mi
5h 5m$57–82Bus, shuttle, drive via Charlotte Airport (CLT)
- Take the bus from Charleston, WV to Charlotte Bus Stationbus
- Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus
- Take a shuttle bus from Boone to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Knoxvillecar
14h 37m$369–434Bus, shuttle, drive
- Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
- Take a shuttle bus from Asheville Airport to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Chilhowee at Holstoncar
15h 59m$409–481
Yeager Airport (CRW) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Charleston to Knoxville is to drive which costs $55 - $85 and takes 5h 5m.
The fastest way to get from Charleston to Knoxville is to fly which takes 4h 2m and costs $190 - $950.
The distance between Charleston and Knoxville is 239 miles. The road distance is 310 miles.
It takes approximately 4h 2m to get from Charleston to Knoxville, including transfers.
Yes, the driving distance between Charleston to Knoxville is 310 miles. It takes approximately 5h 5m to drive from Charleston to Knoxville.
There are 312+ hotels available in Knoxville.
What companies run services between Charleston, WV, USA and Knoxville, TN, USA?
American Airlines, Delta, and United Airlines fly from Yeager Airport (CRW) to Mcghee Tyson Airport (TYS) every 4 hours.
- Website
- delta.com
Flights from Yeager Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $150–900
- Website
- aa.com
Flights from Yeager Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $130–850
- Website
- united.com
Flights from Yeager Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $220–1,100
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $26–70
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Charleston Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Asheville, NC
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- Greyhound
- Phone
- +1 828-327-2340
- [email protected]
- Website
- Hickory Hop
Bus from Charlotte Airport to ASU Peacock Hall Boone
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $90–110
- Schedules at
- Hickory Hop
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Boone to Black Bear Resort
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Hot Springs
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Asheville Airport to Black Bear Resort
- Ave. Duration
- 2h 30m
- Frequency
- On demand
- Estimated price
- $168
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Hot Springs
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
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