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How to get fromCharleston to Louisvilleby bus (Greyhound), train, bus, car, or plane

Find Transport to Louisville

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There are 5 ways to get from Charleston to Louisville by bus (Greyhound), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Charleston Bus Station to Columbusbus bus Greyhound US0140
    2. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus Cleveland
    9h 15m
    $39–115

  2. Train, bus (Amtrak)

    1. Take the train from Charleston Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    12h 11m
    $129–266

  3. Drive 245.9 mi

    1. Drive from Charleston to Louisvillecar car 245.9 mi
    4h 3m
    $45–65

  4. Fly to Louisville International Airport

    1. Fly from Yeager Airport (CRW) to Louisville International Airport (SDF)plane plane CRW - SDF
    5h 51m
    $134–668

  5. Fly to Blue Grass Airport, drive

    1. Fly from Yeager Airport (CRW) to Blue Grass Airport (LEX)plane plane CRW - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 4m
    $186–984

Charleston to Louisville by bus

Calendar14Weekly Buses
Duration9h 15mAverage Duration
Ticket$39Cheapest Price
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Questions & Answers

Map of how to get from Charleston to Louisville.ExpandLaunch map view
  • Distance: 398.9 mi
  • Duration: 9h 15m

What companies run services between Charleston, WV, USA and Louisville, KY, USA?

You can take a bus from Charleston Bus Station to Louisville, KY Bus Station via Columbus - Downtown - Mound St in around 9h 15m. Alternatively, Delta, American Airlines, and United Airlines fly from Yeager Airport (CRW) to Louisville International Airport (SDF) every 4 hours.

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Need to know: Greyhound

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