There are 5 ways to get from Charleston to Murrells Inlet by plane, bus (Greyhound), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Yeager Airport
best- Fly from Yeager Airport (CRW) to Myrtle Beach (MYR)plane CRW - MYR
4h 3m$98–375Drive 425.4 mi
cheapest- Drive from Charleston to Murrells Inletcar 425.4 mi
8h 16m$78–113Bus via Camden
- Take the bus from Charleston to Charlottebus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
12h 26m$120–181Taxi to Tri-State Airport, fly
- Take the taxi from Charleston to Tri-State Airport (HTS)taxi
- Fly from Tri-State Airport (HTS) to Myrtle Beach (MYR)plane HTS - MYR
4h 51m$210–502Bus (Greyhound)
- Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Fayetteville Bus Stationbus
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
14h 31m$132–196
Yeager Airport (CRW) to Myrtle Beach (MYR) flights
Comparing Your Travel Options
The cheapest way to get from Charleston to Murrells Inlet is to drive which costs $75 - $120 and takes 8h 16m.
The fastest way to get from Charleston to Murrells Inlet is to fly which takes 4h 3m and costs $95 - $380.
No, there is no direct bus from Charleston to Murrells Inlet station. However, there are services departing from Charleston and arriving at Myrtle Beach Bus Station via Charlotte Bus Station and Camden. The journey, including transfers, takes approximately 12h 26m.
The distance between Charleston and Murrells Inlet is 376 miles. The road distance is 427.9 miles.
The best way to get from Charleston to Murrells Inlet without a car is to bus via Camden which takes 12h 26m and costs $120 - $190.
It takes approximately 4h 3m to get from Charleston to Murrells Inlet, including transfers.
Charleston to Murrells Inlet bus services, operated by Barons Bus, depart from Charleston station.
The best way to get from Charleston to Murrells Inlet is to fly which takes 4h 3m and costs $95 - $380. Alternatively, you can bus via Camden, which costs $120 - $190 and takes 12h 26m.
Charleston to Murrells Inlet bus services, operated by Barons Bus, arrive at Charlotte station.
Yes, the driving distance between Charleston to Murrells Inlet is 428 miles. It takes approximately 8h 16m to drive from Charleston to Murrells Inlet.
What companies run services between Charleston, WV, USA and Murrells Inlet, SC, USA?
Delta, American Airlines, and United Airlines fly from Yeager Airport (CRW) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Charleston to Murrells Inlet via Charlotte Bus Station, Camden, and Myrtle Beach Bus Station in around 12h 26m.
- Website
- aa.com
Flights from Yeager Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $45–310
Flights from Yeager Airport to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $90–440
Flights from Tri-State Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $50–310
- Website
- delta.com
Flights from Yeager Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $65–360
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charleston to Charlotte
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $26–70
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston to Charlotte
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Camden to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Charleston Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Fayetteville Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $26–40
- Website
- Greyhound
- Ave. Duration
- 1h 1m
- Estimated price
- $120–150
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Booking & Getting There
There are 3137+ hotels available in Murrells Inlet.






