There are 6 ways to get from Charleston to Seneca by plane, taxi, bus, train, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Yeager Airport (CRW) to Greenville–Spartanburg International Airport (GSP)plane CRW - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
4h 54m$233–785Drive 362.2 mi
cheapest- Drive from Charleston to Senecacar 362.2 mi
7h 5m$67–96Bus, train via Wytheville
- Take the bus from Charleston, WV to Wythevillebus
- Take the bus from Wytheville to Charlotte Bus Stationbus
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain
10h 47m$91–229Train (Amtrak)
- Take the train from Charleston Station to Charlottesvilletrain Cardinal
- Take the train from Charlottesville to Clemson Amtrak Stationtrain Crescent
17h 31m$230–478Bus, taxi
- Take the bus from Charleston Bus Station to Charlotte Bus Stationbus
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
- Take the taxi from Taqueria Guadalajara - Greenville to Senecataxi
11h 26m$173–339Bus, train
- Take the bus from Charleston Bus Station to Charlotte Bus Stationbus Greyhound US0140
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain Crescent
11h 27m$97–204
Yeager Airport (CRW) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Charleston to Seneca is to drive which costs $65 - $100 and takes 7h 5m.
The fastest way to get from Charleston to Seneca is to fly and taxi which takes 4h 54m and costs $230 - $800.
No, there is no direct train from Charleston station to Seneca station. However, there are services departing from Charleston Station and arriving at Clemson Amtrak Station via Charlottesville. The journey, including transfers, takes approximately 17h 31m.
The distance between Charleston and Seneca is 298 miles. The road distance is 364.3 miles.
The best way to get from Charleston to Seneca without a car is to bus and train via Wytheville which takes 10h 47m and costs $90 - $230.
It takes approximately 4h 54m to get from Charleston to Seneca, including transfers.
Charleston to Seneca train services, operated by Amtrak, depart from Charleston Station.
Charleston to Seneca train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Charleston to Seneca is 364 miles. It takes approximately 7h 5m to drive from Charleston to Seneca.
Book your Charleston to Seneca train tickets online with Omio.
What companies run services between Charleston, WV, USA and Seneca, SC, USA?
You can take a train from Charleston Station to Seneca via Charlottesville and Clemson Amtrak Station in around 17h 31m.
- Website
- delta.com
Flights from Yeager Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $110–650
- Website
- aa.com
Flights from Yeager Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $90–600
- Website
- united.com
Flights from Yeager Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $40–95
- Website
- Amtrak
Train from Charleston Station to Charlottesville
- Ave. Duration
- 7h 4m
- Frequency
- 3 times a week
- Estimated price
- $85–180
- Website
- Amtrak
Train from Charlottesville to Clemson Amtrak Station
- Ave. Duration
- 9h 15m
- Frequency
- Once daily
- Estimated price
- $120–270
- Website
- Amtrak
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $40–95
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charleston, WV to Wytheville
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $13–50
- Website
- Barons Bus
Bus from Wytheville to Charlotte Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- Barons Bus
Bus from Charleston Bus Station to Charlotte Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $30–75
- Website
- Barons Bus
Bus from Charleston Bus Station to Charlotte Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $30–75
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston Bus Station to Charlotte Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Charleston Bus Station to Charlotte Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
- Ave. Duration
- 56 min
- Estimated price
- $100–170
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
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