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How to get fromCharleston to St. Louisby plane, train, bus, bus (Greyhound), car, or train (Amtrak)

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There are 5 ways to get from Charleston to St. Louis by plane, train, bus, bus (Greyhound), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Yeager Airport (CRW) to Lambert–St. Louis International Airport (STL)plane plane CRW - STL
    5h 10m
    $146–718

  2. Bus

    cheapest
    1. Take the bus from Charleston, WV to Cambridgebus bus Charleston
    2. Take the bus from Cambridge, OH to St Louis Bus Stationbus bus Greyhound US0421
    14h 20m
    $88–198

  3. Train, bus

    1. Take the train from Charleston Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    13h 41m
    $143–291

  4. Drive 504.4 mi

    1. Drive from Charleston to St. Louiscar car 504.4 mi
    8h 18m
    $92–133

  5. Train (Amtrak)

    1. Take the train from Charleston Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    20h 2m
    $262–540

Charleston to St. Louis by train and bus

Calendar3Weekly Services
Duration13h 41mAverage Duration
Ticket$143Cheapest Price
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Questions & Answers

Map of how to get from Charleston to St. Louis.ExpandLaunch map view
  • Distance: 492.6 mi
  • Duration: 5h 10m

What companies run services between Charleston, WV, USA and St. Louis, MO, USA?

Delta, American Airlines, and United Airlines fly from Yeager Airport (CRW) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Charleston, WV to St Louis Bus Station via Cambridge and Cambridge, OH in around 14h 20m.

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