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How to get fromCharlotte Airport (CLT) to Chicagoby plane, bus (Greyhound), train (Amtrak), car, train, or bus (Greyhound, Amtrak)

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There are 8 ways to get from Charlotte Airport (CLT) to Chicago by plane, bus (Greyhound), train (Amtrak), car, train, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    2h 58m
    $131–408

  2. Bus

    cheapest
    1. Take the bus from Charlotte Bus Station to Columbusbus bus Greyhound US0140
    2. Take the bus from Columbus - Mound St to Chicagobus bus Columbus / ...
    20h 16m
    $78–185

  3. Train (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Carytrain train Piedmont / ...
    2. Take the train from Cary to Chicago Union Stationtrain train Floridian
    31h 7m
    $393–865

  4. Drive 724.5 mi

    1. Drive from Charlotte Airport (CLT) to Chicagocar car 724.5 mi
    13h 41m
    $133–191

  5. Fly to Chicago Midway International Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    2h 36m
    $83–436

  6. Fly to South Bend, train

    1. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    4h 56m
    $132–666

  7. Fly to General Mitchell International Airport, train

    1. Fly from Charlotte Douglas International Airport (CLT) to General Mitchell International Airport (MKE)plane plane CLT - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    5h 5m
    $156–732

  8. Bus via Toledo

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    20h 33m
    $173–305

Charlotte Airport (CLT) to Chicago by bus

Calendar14Weekly Buses
Duration20h 16mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Charlotte Airport (CLT) to Chicago.ExpandLaunch map view
  • Distance: 616.7 mi
  • Duration: 2h 58m

What companies run services between Charlotte Airport (CLT), USA and Chicago, IL, USA?

American Airlines and United Airlines fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from Charlotte Douglas Airport to Chicago via Transit Center- Bay V, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, and Columbus - Mound St in around 20h 16m.

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