Rome2Rio

How to get fromCharlotte to St. Louisby plane, taxi, train, bus (Amtrak, Flixbus), car, or bus

Find Transport to St. Louis

See all options

There are 7 ways to get from Charlotte to St. Louis by plane, taxi, train, bus (Amtrak, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Capital Region International Airport

    best
    1. Fly from Capital Region International Airport (LAN) to Lambert–St. Louis International Airport (STL)plane plane LAN - STL
    4h 30m
    $168–730

  2. Drive 462.4 mi

    cheapest
    1. Drive from Charlotte to St. Louiscar car 462.4 mi
    7h 44m
    $85–122

  3. Taxi, train

    1. Take the taxi from Charlotte to Battle Creektaxi taxi
    2. Take the train from Battle Creek to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    9h 15m
    $221–396

  4. Bus

    1. Take the bus from East Lansing Amtrak Station to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    11h 21m
    $193–276

  5. Taxi to Gerald R. Ford International Airport, fly

    1. Take the taxi from Charlotte to Grand-Rapids-Airport-GRRtaxi taxi
    2. Fly from Gerald R. Ford International Airport (GRR) to Lambert–St. Louis International Airport (STL)plane plane GRR - STL
    5h 23m
    $245–776

  6. Bus to Detroit, fly

    1. Take the bus from East Lansing, MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 38m
    $533–1,074

  7. Taxi, bus, train

    1. Take the taxi from Charlotte to Battle Creek Bus Stoptaxi taxi
    2. Take the bus from Battle Creek Bus Stop to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to St. Louistrain train
    10h 30m
    $196–336

Capital Region International Airport (LAN) to Lambert–St. Louis International Airport (STL) flights

Calendar54Weekly Planes
Duration5h 14mAverage Duration
Ticket$107Cheapest Price
See schedules

Questions & Answers

Map of how to get from Charlotte to St. Louis.ExpandLaunch map view
  • Distance: 446.1 mi
  • Duration: 4h 30m

What companies run services between Charlotte, MI, USA and St. Louis, MO, USA?

Delta, American Airlines, and United Airlines fly from Capital Region International Airport (LAN) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a vehicle from Charlotte to St Louis Bus Station via East Lansing Amtrak Station, Chicago Union Station, and Chicago Bus Station in around 11h 21m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers