There are 5 ways to get from Charlotte, NC to Louisville by bus, plane, bus (Flixbus, Greyhound, Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 8 bus, fly to Louisville International Airport
best- Take the bus from Tuckaseegee Rd & Hazel St to Trade St & Graham Stbus
- Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane CLT - SDF
4h 50m$97–611Drive 434.7 mi
cheapest- Drive from Charlotte, NC to Louisvillecar 434.7 mi
8h 59m$80–115Bus via Atlanta
- Take the bus from Charlotte Bus Station to Atlanta Downtownbus
- Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
15h 39m$110–200Fly to Blue Grass Airport, drive
- Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane CLT - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 1m$139–827Bus
- Take the bus from Charlotte Bus Station to Wilson & Ferrell Shell Station - Columbusbus Greyhound US0140
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus Cleveland
16h 55m$92–202
Charlotte, NC to Louisville by foot, bus, and subway
Questions & Answers
The cheapest way to get from Charlotte, NC to Louisville is to drive which costs $75 - $120 and takes 8h 59m.
The fastest way to get from Charlotte, NC to Louisville is to line 8 bus and fly which takes 4h 50m and costs $95 - $650.
No, there is no direct bus from Charlotte, NC to Louisville. However, there are services departing from Tuckaseegee Rd & Hazel St and arriving at Louisville, KY via Charlotte Bus Station, Atlanta Bus Station and Nashville. The journey, including transfers, takes approximately 15h 39m.
The distance between Charlotte, NC and Louisville is 356 miles. The road distance is 437.3 miles.
The best way to get from Charlotte, NC to Louisville without a car is to bus via Atlanta which takes 15h 39m and costs $110 - $200.
It takes approximately 4h 50m to get from Charlotte, NC to Louisville, including transfers.
Charlotte, NC to Louisville bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
Charlotte, NC to Louisville bus services, operated by Flixbus USA, arrive at Atlanta Downtown station.
Yes, the driving distance between Charlotte, NC to Louisville is 437 miles. It takes approximately 8h 59m to drive from Charlotte, NC to Louisville.
There are 606+ hotels available in Louisville.
What companies run services between Charlotte, NC, USA and Louisville, KY, USA?
You can take a vehicle from Charlotte, NC to Louisville, KY via Tuckaseegee Rd & Hazel St, Trade St & Graham St, Charlotte Bus Station, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Nashville in around 15h 39m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Louisville International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $90–600
Flights from Charlotte Douglas International Airport to Blue Grass Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $120–800
- Phone
- +1 704-336-7433
- [email protected]
- Website
- charlottenc.gov
Bus from Tuckaseegee Rd & Hazel St to Trade St & Graham St
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1–3
- Website
- https://www.charlottenc.gov/CATS/Home
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Charlotte Bus Station to Atlanta Downtown
- Ave. Duration
- 4h 10m
- Frequency
- 4 times a week
- Estimated price
- $40–70
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 10h 25m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- https://baronsbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide











