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How to get fromCharlotte Station (Amtrak) to Des Moinesby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 8 ways to get from Charlotte Station (Amtrak) to Des Moines by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charlotte Douglas International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    4h 45m
    $192–876

  2. Bus via Columbus

    cheapest
    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    28h 58m
    $127–307

  3. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    27h 46m
    $182–362

  4. Train, bus

    1. Take the train from Charlotte Amtrak Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    32h 41m
    $344–713

  5. Drive 1,029.4 mi

    1. Drive from Charlotte Station (Amtrak) to Des Moinescar car 1,029.4 mi
    17h 43m
    $188–272

  6. Train to Piedmont Triad International Airport, fly

    1. Take the train from Charlotte Amtrak Station to High Pointtrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Des Moines (DSM)plane plane GSO - DSM
    8h
    $252–1,046

  7. Train, bus via Chicago

    1. Take the train from Charlotte Amtrak Station to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    36h 52m
    $442–953

  8. Train, bus via Galesburg

    1. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    38h 15m
    $475–1,033

Charlotte Station (Amtrak) to Des Moines by foot and bus

Calendar14Weekly Services
Duration27h 46mAverage Duration
Ticket$182Cheapest Price
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Questions & Answers

Map of how to get from Charlotte Station (Amtrak) to Des Moines.ExpandLaunch map view
  • Distance: 830 mi
  • Duration: 4h 45m

What companies run services between Charlotte Station (Amtrak), NC, USA and Des Moines, IA, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM) every 2 hours. Alternatively, you can take a vehicle from Charlotte Station (Amtrak) to Des Moines via Graham St & Keswick Ave, Trade St & Graham St, Charlotte Bus Station, Atlanta Bus Station, and St Louis Bus Station in around 27h 46m.

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