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How to get fromCharlotte to Buffaloby plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Charlotte to Buffalo by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    4h 7m
    $124–731

  2. Bus

    cheapest
    1. Take the bus from Charlotte Bus Station to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Cleveland, OHbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    16h 40m
    $87–211

  3. Train (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    22h 46m
    $312–663

  4. Drive 653.8 mi

    1. Drive from Charlotte to Buffalocar car 653.8 mi
    11h 11m
    $120–173

  5. Fly to Rochester, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane plane CLT - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 49m
    $171–845

  6. Bus via Newark

    1. Take the bus from Charlotte Bus Station to Newark Penn Stationbus bus Greyhound US0700 / ...
    2. Take the bus from Newark Penn Station to Buffalobus bus FlixBus 2686 / ...
    21h 25m
    $147–293

Charlotte to Buffalo by bus

Calendar7Weekly Buses
Duration16h 40mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Buffalo.ExpandLaunch map view
  • Distance: 567.7 mi
  • Duration: 4h 7m

What companies run services between Charlotte, NC, USA and Buffalo, NY, USA?

American Airlines, Southwest Airlines, and United Airlines fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to Buffalo, NY via Charleston, WV and Cleveland, OH in around 16h 40m.

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