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How to get fromCharlotte to Cape Girardeauby plane, bus, taxi, car, bus (Greyhound, Flixbus), or bus (Greyhound)

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There are 9 ways to get from Charlotte to Cape Girardeau by plane, bus, taxi, car, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport, bus

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 14m
    $139–699

  2. Drive 604.1 mi

    cheapest
    1. Drive from Charlotte to Cape Girardeaucar car 604.1 mi
    10h 49m
    $111–160

  3. Bus, taxi via Atlanta

    1. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    14h 40m
    $218–329

  4. Fly to Cape Girardeau Municipal Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to Cape Girardeau Municipal Airport (CGI)plane plane CLT - CGI
    6h 27m
    $135–580

  5. Fly to Memphis, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Memphis (MEM)plane plane CLT - MEM
    2. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    8h 48m
    $167–817

  6. Fly to Nashville, bus, taxi

    1. Fly from Charlotte Douglas International Airport (CLT) to Nashville (BNA)plane plane CLT - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    9h 23m
    $524–994

  7. Bus, taxi

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    15h 1m
    $213–331

  8. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    17h 54m
    $127–245

  9. Bus via Sandy Springs

    1. Take the bus from Charlotte to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    21h 5m
    $154–349

Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) flights

Calendar56Weekly Planes
Duration2h 58mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Cape Girardeau.ExpandLaunch map view
  • Distance: 711.2 mi
  • Duration: 7h 14m

What companies run services between Charlotte, NC, USA and Cape Girardeau, MO, USA?

American Airlines, Corporate Flight Management Inc, and two other airlines fly from Charlotte Douglas International Airport (CLT) to Cape Girardeau Municipal Airport (CGI) twice daily. Alternatively, you can take a bus from Charlotte Bus Station to Cape Girardeau via Atlanta Bus Station, Memphis Bus Station, and Cape Girardeau in around 17h 54m.

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