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How to get fromCharlotte to Chicagoby plane, bus (Greyhound, Amtrak), train (Amtrak), car, train, or bus

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There are 9 ways to get from Charlotte to Chicago by plane, bus (Greyhound, Amtrak), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlotte Douglas International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    4h 25m
    $124–417

  2. Bus via Hurricane

    cheapest
    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    20h 10m
    $76–209

  3. Bus

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    19h 2m
    $180–305

  4. Train (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Carytrain train Piedmont / ...
    2. Take the train from Cary to Chicago Union Stationtrain train Floridian
    29h 13m
    $404–807

  5. Drive 741.7 mi

    1. Drive from Charlotte to Chicagocar car 741.7 mi
    12h 54m
    $136–196

  6. Fly Charlotte Douglas International Airport to Chicago Midway International Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    4h 3m
    $84–447

  7. Fly Charlotte Douglas International Airport to South Bend, train

    1. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    6h 23m
    $135–717

  8. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Charlotte Amtrak Station to High Pointtrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    6h 23m
    $118–480

  9. Fly Charlotte Douglas International Airport to General Mitchell International Airport, train

    1. Fly from Charlotte Douglas International Airport (CLT) to General Mitchell International Airport (MKE)plane plane CLT - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    6h 32m
    $161–821

Charlotte to Chicago by bus

Calendar2Weekly Buses
Duration19h 2mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Chicago.ExpandLaunch map view
  • Distance: 624.4 mi
  • Duration: 4h 25m

What companies run services between Charlotte, NC, USA and Chicago, IL, USA?

American Airlines and United Airlines fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from Charlotte Bus Station to Chicago Union Station via Toledo in around 19h 2m.

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