Rome2Rio

How to get fromCharlotte to Key West (Island)by plane, bus (Flixbus, Greyhound), bus, train, car, or ferry

Find Transport to Key West (Island)

See all options

There are 7 ways to get from Charlotte to Key West (Island) by plane, bus (Flixbus, Greyhound), bus, train, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charlotte Douglas International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane plane CLT - EYW
    3h 48m
    $67–352

  2. Bus

    1. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    21h 23m
    $138–217

  3. Bus, train

    1. Take the bus from Charlotte Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    27h 56m
    $500–780

  4. Drive  882.8 mi

    1. Drive from Charlotte to Key Westcar car 882.8 mi
    15h 26m
    $162–233

  5. Fly from Concord

    1. Fly from Concord (USA) to Key West International Airport (EYW)plane plane USA - EYW
    6h 5m
    $92–382

  6. Bus, ferry

    1. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    24h 40m
    $241–306

  7. Train, bus

    1. Take the train from Charlotte Amtrak Station to Carytrain train
    2. Take the train from Cary to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    32h 8m
    $619–1,036

Charlotte to Key West (Island) by bus

Calendar7Weekly Buses
Duration21h 23mAverage Duration
Ticket$138Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Charlotte to Key West (Island).ExpandLaunch map view
  • Distance: 746.4 mi
  • Duration: 3h 48m

What companies run services between Charlotte, NC, USA and Key West (Island), FL, USA?

American Airlines and Delta fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to Key West Airport via Orlando Bus Station and Miami Airport Station in around 21h 23m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There