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How to get fromCharlotte to La Crosseby plane, bus (Greyhound, Amtrak), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Charlotte to La Crosse by plane, bus (Greyhound, Amtrak), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to La Crosse

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to La Crosse (LSE)plane plane CLT - LSE
    6h 26m
    $106–485

  2. Bus

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus
    2. Take the bus from Toledo to Chicago Union Stationbus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to La Crossebus bus
    26h 39m

  3. Train (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    35h 12m
    $791–1,329

  4. Drive  1,023.1 mi

    1. Drive from Charlotte to La Crossecar car 1,023.1 mi
    17h 34m
    $169–244

  5. Fly to Dane County Regional Airport-Truax Field, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Dane County Regional Airport-Truax Field (MSN)plane plane CLT - MSN
    2. Take the bus from Madison to La Crossebus bus
    8h 4m
    $119–499

  6. Bus via Columbus

    1. Take the bus from Charlotte to Columbusbus bus
    2. Take the bus from Columbus to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    26h 39m
    $170–287

Charlotte Douglas International Airport (CLT) to La Crosse (LSE) flights

Calendar60Weekly Planes
Duration7h 25mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from Charlotte to La Crosse.ExpandLaunch map view
  • Distance: 826.2 mi
  • Duration: 6h 26m

What companies run services between Charlotte, NC, USA and La Crosse, WI, USA?

American Airlines flies from Charlotte Douglas International Airport (CLT) to La Crosse (LSE) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to La Crosse via Toledo, Chicago Union Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, and Madison in around 26h 39m.

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Want to know more about travelling around United States

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