There are 7 ways to get from Charlotte to Lake City by bus (Flixbus, Greyhound), car, plane, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Charlotte Bus Station to Jacksonvillebus FlixBus 2433
- Take the bus from Jacksonville to Lake City Bus Stationbus Greyhound US0760S
9h 25m$70–132Drive 433.1 mi
- Drive from Charlotte to Lake Citycar 433.1 mi
7h 23m$79–115Fly to Jacksonville, bus
- Fly from Charlotte Douglas International Airport (CLT) to Jacksonville (JAX)plane CLT - JAX
- Take the bus from Jacksonville to Lake City Bus Stationbus
6h 21m$77–443Bus via Camden
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Jacksonvillebus
- Take the bus from Jacksonville to Lake City Bus Stationbus
12h 5m$71–152Fly to Gainesville Regional Airport, bus
- Fly from Charlotte Douglas International Airport (CLT) to Gainesville Regional Airport (GNV)plane CLT - GNV
- Take the bus from Gainesville to Lake City Bus Stationbus
6h 29mFly to Tallahassee, bus
- Fly from Charlotte Douglas International Airport (CLT) to Tallahassee (TLH)plane CLT - TLH
- Take the bus from Tallahassee to Lake City Bus Stationbus
6h 40m$121–555Fly to Orlando, bus
- Fly from Charlotte Douglas International Airport (CLT) to Orlando (MCO)plane CLT - MCO
- Take the bus from Orlando Bus Station to Lake City Bus Stationbus
9h 6m$130–396
Charlotte to Lake City by bus
Questions & Answers
The cheapest way to get from Charlotte to Lake City is to bus which costs $70 - $140 and takes 9h 25m.
The fastest way to get from Charlotte to Lake City is to fly and bus which takes 6h 21m and costs $75 - $450.
No, there is no direct bus from Charlotte station to Lake City station. However, there are services departing from Charlotte Bus Station and arriving at Lake City Bus Station via Jacksonville. The journey, including transfers, takes approximately 9h 25m.
The distance between Charlotte and Lake City is 446 miles. The road distance is 435.6 miles.
The best way to get from Charlotte to Lake City without a car is to bus which takes 9h 25m and costs $70 - $140.
It takes approximately 9h 25m to get from Charlotte to Lake City, including transfers.
Charlotte to Lake City bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
Charlotte to Lake City bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Charlotte to Lake City is 436 miles. It takes approximately 7h 23m to drive from Charlotte to Lake City.
Book your Charlotte to Lake City bus tickets online with Omio and FlixBus.
What companies run services between Charlotte, NC, USA and Lake City, FL, USA?
You can take a bus from Charlotte Bus Station to Lake City Bus Station via Jacksonville in around 9h 25m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Jacksonville
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $65–420
Flights from Charlotte Douglas International Airport to Gainesville Regional Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $65–400
Flights from Charlotte Douglas International Airport to Tallahassee
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $80–490
Flights from Charlotte Douglas International Airport to Orlando
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $70–410
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Jacksonville via Atlanta
- Ave. Duration
- 3h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–470
Flights from Charlotte Douglas International Airport to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $80–440
Flights from Charlotte Douglas International Airport to Tallahassee via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $90–550
- Website
- flyfrontier.com
Flights from Charlotte Douglas International Airport to Orlando
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $100–340
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Charlotte Bus Station to Jacksonville
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Charlotte Bus Station to Jacksonville
- Ave. Duration
- 9h 10m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Jacksonville to Lake City Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $9–18
- Website
- https://www.greyhound.com/
Bus from Jacksonville to Lake City Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $9–18
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
Bus from Camden to Jacksonville
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Jacksonville to Lake City Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $9–18
- Website
- https://www.greyhound.com/
Bus from Tallahassee to Lake City Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $16–35
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Lake City Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $24–50
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Jacksonville to Lake City Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Jacksonville to Lake City Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Jacksonville to Lake City Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Tallahassee to Lake City Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Orlando Bus Station to Lake City Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Schedules at
- greyhound.com
- Website
- flixbus.com
Bus from Gainesville to Lake City Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Lake City Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Schedules at
- flixbus.com
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