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How to get fromCharlotte to Louisvilleby plane, bus (Flixbus, Greyhound, Amtrak), train, bus, car, bus (Greyhound, Flixbus, Amtrak), or bus (Amtrak)

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There are 8 ways to get from Charlotte to Louisville by plane, bus (Flixbus, Greyhound, Amtrak), train, bus, car, bus (Greyhound, Flixbus, Amtrak), or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    4h 3m
    $93–605

  2. Fly to Blue Grass Airport, drive

    cheapest
    1. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 11m
    $65–351

  3. Bus via Atlanta

    1. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    14h 14m
    $104–172

  4. Train, bus (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 41m
    $497–817

  5. Drive  437.5 mi

    1. Drive from Charlotte to Louisvillecar car 437.5 mi
    9h 4m
    $80–116

  6. Fly to Dayton, drive

    1. Fly from Charlotte Douglas International Airport (CLT) to Dayton (DAY)plane plane CLT - DAY
    2. Drive from Dayton-Airport-DAY to Louisvillecar car
    5h 58m
    $86–397

  7. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    14h 20m
    $101–176

  8. Bus #2

    1. Take the bus from Charlotte to Columbusbus bus
    2. Take the bus from Columbus to Cincinnatibus bus
    3. Take the bus from Cincinnati to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    20h 25m
    $93–240

Charlotte to Louisville by bus and subway

Calendar4Weekly Services
Duration14h 14mAverage Duration
Ticket$104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Charlotte to Louisville.ExpandLaunch map view
  • Distance: 349.3 mi
  • Duration: 4h 3m

What companies run services between Charlotte, NC, USA and Louisville, KY, USA?

American Airlines, Southwest Airlines, and Delta fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to Louisville, KY via Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Nashville in around 14h 14m.

Airlines
Train operators
Bus operators

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