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How to get fromCharlotte to Louisville, KYby plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Charlotte to Louisville, KY by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    4h 32m
    $93–605

  2. Bus #2

    cheapest
    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    17h 5m
    $67–189

  3. Bus via Atlanta

    1. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus Greyhound US0105 / ...
    14h 29m
    $108–199

  4. Drive 438.7 mi

    1. Drive from Charlotte to Louisville, KYcar car 438.7 mi
    9h 6m
    $81–116

  5. Fly to Blue Grass Airport, drive

    1. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    2. Drive from Lexington-Airport-LEX to Louisville, KYcar car
    4h 13m
    $135–822

  6. Fly to Covington, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Covington (CVG)plane plane CLT - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    6h 41m
    $108–649

  7. Fly to Evansville, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Evansville (EVV)plane plane CLT - EVV
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    6h 43m
    $122–492

  8. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus Greyhound US0105 / ...
    14h 50m
    $102–201

Charlotte to Louisville, KY by bus and subway

Calendar4Weekly Services
Duration14h 29mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Louisville, KY.ExpandLaunch map view
  • Distance: 351.6 mi
  • Duration: 4h 32m

What companies run services between Charlotte, NC, USA and Louisville, KY, USA?

American Airlines flies from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF) 5 times a day. Alternatively, you can take a bus from Charlotte Bus Station to Louisville Bus Station via Atlanta Downtown, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 14h 29m.

Airlines
Bus operators

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