There are 6 ways to get from Charlotte to Mississauga by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Toronto Pearson International Airport
best- Fly from Charlotte Douglas International Airport (CLT) to Toronto Pearson International Airport (YYZ)plane CLT - YYZ
4h 53m$98–560Bus
- Take the bus from Charlotte Bus Station to Detroit Bus Stationbus Greyhound US0140
- Take the bus from Detroit Bus Station to Mississaugabus FlixBus N2706
22h$217–320Train
- Take the train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain Crescent / ...
- Take the train from New York Penn Station to Oakvilletrain VIA Rail
27h 2m$671–1,184Drive 1,189.2 km
- Drive from Charlotte to Mississaugacar 1,189.2 km
12h 41m$240–346Fly to Buffalo Niagara International Airport, bus
- Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane CLT - BUF
- Take the bus from Buffalo to Mississaugabus
7h 14m$177–939Bus via Columbus
- Take the bus from Charlotte to Columbusbus
- Take the bus from Columbus to Buffalobus
- Take the bus from Buffalo to Mississaugabus
23h 7m$151–342
Charlotte to Mississauga by bus
Comparing Your Travel Options
The cheapest way to get from Charlotte to Mississauga is to bus which costs $210 - $320 and takes 22h.
The fastest way to get from Charlotte to Mississauga is to fly which takes 4h 53m and costs $95 - $600.
No, there is no direct bus from Charlotte station to Mississauga. However, there are services departing from Charlotte Bus Station and arriving at Mississauga via Detroit Bus Station. The journey, including transfers, takes approximately 22h.
No, there is no direct train from Charlotte station to Mississauga. However, there are services departing from Charlotte Amtrak Station and arriving at Clarkson GO via New York Penn Station and Oakville GO. The journey, including transfers, takes approximately 27h 2m.
The distance between Charlotte and Mississauga is 975 km. The road distance is 1189.2 km.
The best way to get from Charlotte to Mississauga without a car is to bus which takes 22h and costs $210 - $320.
It takes approximately 4h 53m to get from Charlotte to Mississauga, including transfers.
Charlotte to Mississauga bus services, operated by Greyhound USA, depart from Charlotte Bus Station.
Charlotte to Mississauga train services, operated by Amtrak, depart from Charlotte Amtrak Station.
The best way to get from Charlotte to Mississauga is to fly which takes 4h 53m and costs $95 - $600. Alternatively, you can bus, which costs $210 - $320 and takes 22h, you could also train, which costs $650 - $1,200 and takes 27h 2m.
What companies run services between Charlotte, NC, USA and Mississauga, ON, Canada?
American Airlines, Air Canada, and two other airlines fly from Charlotte Douglas International Airport (CLT) to Toronto Pearson International Airport (YYZ) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to Mississauga via Detroit Bus Station in around 22h.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $90–550
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $140–850
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $170–950
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $160–900
- Website
- united.com
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $90–550
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $95–550
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 55m
- When
- Sunday, Thursday, Monday, Wednesday, and Friday
- Estimated price
- $150–900
- Website
- aircanada.com
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $90–550
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $95–550
- Website
- southwest.com
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- $160–900
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport via Detroit
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 13h 11m
- Frequency
- Twice daily
- Estimated price
- $470–750
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Oakville
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $190–450
- Website
- VIA Rail
- Escape
- $190–430
- Business
- $250–420
- Business Plus
- $270–440
- Economy
- $220–440
- Economy Plus
- $240–450
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charlotte Bus Station to Detroit Bus Station
- Ave. Duration
- 15h 10m
- Frequency
- Once daily
- Estimated price
- $160–250
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Detroit Bus Station to Mississauga
- Ave. Duration
- 5h 50m
- Frequency
- 5 times a week
- Estimated price
- $50–75
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Mississauga
- Saver
- $30–75
- Flexible
- $60–80
Bus from Buffalo to Mississauga
- Saver
- $28–70
- Flexible
- $55–75
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charlotte to Columbus
- Ave. Duration
- 11h 5m
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- Barons Bus
Bus from Columbus to Buffalo
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $50–120
- Website
- Barons Bus
Want to know more about travelling around Canada
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Charlotte to Mississauga bus services, operated by Greyhound USA, arrive at Detroit Bus Station.
Charlotte to Mississauga train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Charlotte to Mississauga is 1189 km. It takes approximately 12h 41m to drive from Charlotte to Mississauga.
Book your Charlotte to Mississauga bus tickets online with Omio and FlixBus.
There are 1905+ hotels available in Mississauga.



















