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How to get fromCharlotte to Port Saint Lucieby plane, taxi, bus (Flixbus), car, bus, or bus (Greyhound)

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There are 9 ways to get from Charlotte to Port Saint Lucie by plane, taxi, bus (Flixbus), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Vero Beach Municipal Airport, taxi

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Vero Beach Municipal Airport (VRB)plane plane CLT - VRB
    2. Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi taxi
    4h 15m
    $192–662

  2. Bus via Jacksonville (Greyhound)

    cheapest
    1. Take the bus from Charlotte Bus Station to Camdenbus bus
    2. Take the bus from Camden to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Port St Luciebus bus
    18h 49m
    $97–198

  3. Bus

    1. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus FlixBus 2433
    2. Take the bus from Orlando to Fort Piercebus bus Orlando to Miami
    14h 37m
    $117–182

  4. Drive 613.4 mi

    1. Drive from Charlotte to Port Saint Luciecar car 613.4 mi
    10h 12m
    $112–162

  5. Fly to Melbourne International Airport, taxi, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Melbourne International Airport (MLB)plane plane CLT - MLB
    2. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    3. Take the bus from Sebastian to Port St Luciebus bus
    7h 23m
    $168–555

  6. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CLT - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    7h 6m
    $107–377

  7. Fly to Orlando, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Orlando (MCO)plane plane CLT - MCO
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    7h 39m
    $136–386

  8. Fly to President Donald J. Trump International Airport, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to President Donald J. Trump International Airport (PBI)plane plane CLT - PBI
    2. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    7h 40m
    $106–569

  9. Bus via SW Gatlin Blvd & SW Brescia St (Flixbus)

    1. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus FlixBus 2433
    2. Take the bus from Orlando Bus Station to Port St Luciebus bus FlixBus N2401 / ...
    15h 4m
    $106–175

Charlotte to Port Saint Lucie by bus

Calendar7Weekly Buses
Duration14h 37mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Port Saint Lucie.ExpandLaunch map view
  • Distance: 558.7 mi
  • Duration: 4h 15m

What companies run services between Charlotte, NC, USA and Port Saint Lucie, FL, USA?

You can take a bus from Charlotte Bus Station to Fort Pierce via Orlando Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St, L B Mcleod Rd & Gardenia Ave, and Orlando in around 14h 37m.

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