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How to get fromCharlotte to Saint Charlesby plane, bus (Flixbus, Greyhound), car, bus (Greyhound, Flixbus), or bus (Greyhound)

Find Transport to Saint Charles

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There are 5 ways to get from Charlotte to Saint Charles by plane, bus (Flixbus, Greyhound), car, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    4h 29m
    $126–656

  2. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    17h 15m
    $127–247

  3. Drive 730 mi

    1. Drive from Charlotte to Saint Charlescar car 730 mi
    12h 30m
    $134–193

  4. Bus via Charlotte

    1. Take the bus from Charlotte to Atlanta Bus Stationbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    17h 30m
    $152–261

  5. Bus via Columbus

    1. Take the bus from Charlotte Bus Station to Columbusbus bus Greyhound US0140 / ...
    2. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    21h 35m
    $145–294

Charlotte to Saint Charles by bus and train

Calendar19Weekly Services
Duration17h 15mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Saint Charles.ExpandLaunch map view
  • Distance: 595.5 mi
  • Duration: 4h 29m

What companies run services between Charlotte, NC, USA and Saint Charles, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Charlotte Bus Station to 4375 Rider Trail North Sb via Atlanta Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 17h 15m.

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