There are 3 ways to get from Charlotte to Saint Charles by plane, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane CLT - STL
4h 39m$112–576Bus
- Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus Greyhound US0670 / ...
- Take the bus from Atlanta Bus Station to St Louis Bus Stationbus Greyhound US0186
18h 39m$136–236Drive 730 mi
- Drive from Charlotte to Saint Charlescar 730 mi
12h 30m$134–193
Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Charlotte to Saint Charles is to drive which costs $130 - $200 and takes 12h 30m.
The fastest way to get from Charlotte to Saint Charles is to fly which takes 4h 39m and costs $110 - $600.
No, there is no direct bus from Charlotte station to Saint Charles. However, there are services departing from Charlotte Bus Station and arriving at 4375 Rider Trail North Sb via Atlanta Bus Station and North Hanley Transit Center. The journey, including transfers, takes approximately 18h 39m.
The distance between Charlotte and Saint Charles is 605 miles. The road distance is 734.3 miles.
The best way to get from Charlotte to Saint Charles without a car is to bus which takes 18h 39m and costs $130 - $240.
It takes approximately 4h 39m to get from Charlotte to Saint Charles, including transfers.
Charlotte to Saint Charles bus services, operated by Greyhound USA, depart from Charlotte Bus Station.
The best way to get from Charlotte to Saint Charles is to fly which takes 4h 39m and costs $110 - $600. Alternatively, you can bus, which costs $130 - $240 and takes 18h 39m.
Charlotte to Saint Charles bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Saint Charles is 1h behind Charlotte. It is currently 8:09 AM in Charlotte and 7:09 AM in Saint Charles.
What companies run services between Charlotte, NC, USA and Saint Charles, MO, USA?
American Airlines, Southwest Airlines, and Delta fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to Saint Charles via Atlanta Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 18h 39m.
- Website
- southwest.com
Flights from Charlotte Douglas International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $90–550
Flights from Charlotte Douglas International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 41m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Flights from Charlotte Douglas International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 17m
- When
- Tuesday and Wednesday
- Estimated price
- $110–600
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $90–550
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $100–600
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charlotte Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $90–150
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Charlotte Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 21m
- Frequency
- 5 times a week
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Charlotte to Saint Charles is 734 miles. It takes approximately 12h 30m to drive from Charlotte to Saint Charles.
There are 233+ hotels available in Saint Charles.